The role of amylin in Parkinson´s disease neurodegenerative process
Objective: We investigate the functional interaction between two amyloidogenic (amylin and synuclein) proteins as a potential mechanism for neurodegeneration in Parkinson disease (PD). Background: PD…Age-dependent multisystem parkinsonian features in a novel neuromelanin-producing transgenic mouse model
Objective: We aim to characterize the consequences of age-dependent intracellular neuromelanin accumulation in catecholaminergic neuronal populations to understand the relationship between this process and the…Deep learning based detection of Parkinson’s disease (PD) in Magnetic Resonance Imaging (MRI) brain scans
Objective: To use a deep learning based framework to classify MRI brain scans as PD or control cases. Background: The Parkinson’s Progression Markers Initiative provides…Tractography Analysis of the Pedunculopontine Nucleus Correlates with Gait Impairment in Parkinson’s Disease
Objective: Our objective was to correlate pedunculopontine nucleus (PPN) connectivity with quantitative gait metrics in Parkinson’s disease (PD) using diffusion tensor imaging (DTI). Background: Gait…Altered glymphatic function in Parkinson’s disease
Objective: To examine glymphatic function in Parkinson’s disease utilizing the “Diffusion Tensor Image Analysis aLong the Perivascular Space (DTI-ALPS)” method. Background: Dysfunction of glymphatic system…Neuroanatomical signatures of genetic risk for Parkinson’s Disease in healthy adults
Objective: To determine whether there is a relationship between genetic risk for Parkinson’s disease (PD) and brain structure in healthy adults. Background: PD pathology begins…Patient classification for adaptive deep brain stimulation
Objective: To explore a control theory modeling framework to classify which Parkinson’s disease patients may benefit from adaptive deep brain stimulation. Background: Deep brain stimulation…Links between Cognitive Impairment and Contrast Sensitivity in Parkinson’s Disease
Objective: To evaluate the relationship between Contrast Sensitivity (CS) and cognitive function in patients with idiopathic Parkinson’s Disease (PD) and healthy controls (HC). Background: In…Anxiety and depression in patients with Parkinson’s disease selected for magnetic resonance-guided focused ultrasound thalamotomy.
Objective: To assess the severity of anxiety and depression in patients selected for treatment with the magnetic resonance-guided focused ultrasound thalamotomy (MRgFUS TT) before the…Dopamine dysregulation syndrome in Parkinson’s disease after COVID-19. Case report.
Objective: To describe a case of a man with Parkinson’s disease (PD), who was developed dopamine dysregulation syndrome (DDS) after COVID-19. Background: Parkinson’s disease is…
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