Measuring progression of Parkinson’s disease cardinal signs in the Phase 2 SPARK study
Objective: To evaluate a novel quantitative measure of Parkinson’s disease (PD) severity and progression in a Phase II clinical trial. Background: Cinpanemab, a monoclonal antibody,…Randomised Controlled Trial Comparing Efficacy of Zonisamide 25 mg given in addition to standard treatment with standard treatment alone in Tremor dominant Parkinson’s Disease- A Pilot study.
Objective: To compare improvement in tremor at 12 weeks with Zonisamide given in a dose of 25 mg along with other ant- parkinsonian drugs as…Effect of Ketone Ester Supplementation on Motor and Non-Motor symptoms in Parkinson’s Disease
Objective: To investigate the effect of exogenous ketone ester supplementation on motor and non-motor symptoms in Parkinson’s Disease (PD). Background: Animal research and human pilot…THE EFFECT OF VITAMIN D IN PARKINSON’S DISEASE
Objective: The objective of this study is to investigate the role of vitamin D deficiency (VDD) as an etiopathological factor in Parkinson's disease (PD). Background:…Influence of Dopamine Transporter Gene Polymorphism on Wearing Off
Objective: To study the influence of Dopamine transporter gene polymorphism on Wearing off (WO) through 19 items wearing off questionnaire (WOQ-19) Background: The dopamine transporter…Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of monoamine-oxidase-B inhibitors (MAO-B) and dopamine agonists (DA): findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of monoamine-oxidase-B…Comparison and analysis of pupillometer parameters between patients with drug naive Parkinson’s disease and controls
Objective: We compared the pupillary findings of drug-naïve Parkinson’s disease (PD) patients and controls to investigate the characteristics of pupillary light reflexes (PLR) in PD…ELECTRICAL ACTIVITY OF THE MASTICATORY MUSCLES OF PARKINSONIANS INFLUENCED BY THE USE OF REMOVABLE DENTAL PROSTHESIS
Objective: Analyze the influence of the types of dental prosthesis on the electromyographic activity of the masticatory muscles; masseter and temporal anterior in parkinsonians. Background:…Cardiovascular risk factors and phenoconversion to neurodegenerative synucleinopathies in idiopathic REM sleep behavior disorder
Objective: To evaluate the predictive role of cardiovascular diseases and metabolic risk factors in the phenoconversion of idiopathic REM sleep behavior disorder (iRBD) patients. Background:…Motor skills of walking in Parkinson’s disease: towards a better understanding of the cognitive abilities implicated in F8WT.
Objective: to evaluate disease related and cognitive features involved in motor skills of walking in people with Parkinson’s disease (PWP). Background: curved path walking and…
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