MicroRNAs as a potential biomarker of Parkinson’s disease
Objective: Our study was aimed at analyzing the role of microRNA as a potential biomarker of PD. Background: A substantial part of cases of Parkinson’s…VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease
Objective: To establish the pathogenic effects of the PD-causing VPS35 D620N mutation in vivo and address possible underlying mechanisms. Background: D620N mutation in the vacuolar…Changes in brain functional connectivity after cognitive behavioral therapy for anxiety in Parkinson’s disease: a longitudinal MRI study.
Objective: To identify changes in brain functional connectivity (FC) after Cognitive Behavioral Therapy (CBT) for anxiety in patients with Parkinson’s disease (PD). Background: Recently we…Longitudinal changes in nigral neuromelanin in early, levodopa-treated Parkinson’s disease
Objective: To assess longitudinal changes in neuromelanin (NM) content in the substantia nigra compacta (SNc) and its lateral-ventral subregion in Parkinson’s disease (PD). Background: NM-sensitive…Reduced cerebral energy metabolism in Parkinson’s disease in contrast to Progressive Supranuclear Palsy
Objective: To determine the significance of 31P-MRSI to differentiate between idiopathic Parkinson’s disease (PD), Progressive supranuclear palsy (PSP), and healthy control subjects. Background: Bioenergetic disturbances,…The role of network connectivity in shaping the progression of cortical atrophy in Parkinson’s disease
Objective: We aimed to map the progression of cortical thinning and to test whether this pattern is constrained by network connectivity in the brain. Background:…Emotional stress exacerbates parkinsonian resting tremor
Objective: To examine the role emotions may play in modulating the characteristics of parkinsonian resting tremor. Background: There is ample evidence showing cognitive stress can…Locus coeruleus volume is reduced in Parkinson disease-related orthostatic hypotension.
Objective: To test whether structural pathology of the locus coeruleus (LC) is associated with orthostatic hypotension (OH) in Parkinson disease (PD). Background: OH is an…The prevalence of sarcopenia in Parkinson’s disease and related disorders
Objective: To systematically review the prevalence of sarcopenia in Parkinson’s disease (PD) and atypical parkinsonian syndromes (aPS), how prevalence differs with PD stage and between…GASTROINTESTINAL SYMPTOMS ARE ASSOCIATED WITH LEFT PREDOMINANT DOPAMINE TRANSPORTER BINDING DEFICIT IN PARKINSON´S DISEASE
Objective: To assess correlations between functional gastrointestinal (GI) symptoms and nigrostriatal dopamine transporter imaging asymmetry in Parkinson´s disease (PD) patients. Based on a theory that…
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