Effect of H. pylori Infection on L-DOPA Pharmacokinetics in Patients with Parkinson’s disease.
Objective: To evaluate whether Helicobactor pylori (H.pylori) infection affects the pharmacokinetics of L-DOPA in patients with Parkinson’s disease (PD). Background: H. pylori infects gastric mucosa…Pilot study of Phenotype of Antisense-Oligonucleotide-(ASO)-knockdown of Cerebral-Dopamine-Neurotrophic-Factor (CDNF) as Parkinson Disease model : implications for PD and related Dementia Therapeutics
Objective: Our objective is twofold: 1)to examine whether CDNF-ASO paradigm can induce a unique phenotype mimicking PD/PDD/LBW in the rodent species; 2) to evaluate whether…Coffee, smoking and aspirin are associated with age at onset and clinical severity in idiopathic Parkinson’s disease
Objective: To investigate a possible association between smoking, the consumption of caffeine and the use of aspirin on age at onset (AAO), motor and non-motor…Early Observations of Using a Chronically Implanted INS that can Sense Local Field Potentials in Movement Disorder Patients
Objective: The objective of this study is to report early findings from movement disorder and epilepsy patients that have been implanted with an INS device…Sleep disorders and future diagnosis of parkinsonism: a prospective study using the Canadian Longitudinal Study on Aging
Objective: To determine whether symptoms of insomnia, somnolence, apnea, and restless legs syndrome predict the diagnosis of parkinsonism after three years of follow-up. Background: Earlier…Sociodemographic, cognitive, and clinical factors explaining financial-arithmetic errors in Parkinson’s Disease
Objective: To assess the frequency, predictors, and affected cognitive representations of arithmetic errors in financial contexts in Parkinson’s Disease (PD), patients with normal cognition (PD-NC)…A prospective study of Parkinson’s disease progression towards dementia – dynamics and defining motor features
Objective: Our goal was to investigate the rate of progression to dementia (PDD) in our cohort of Parkinson’s disease (PD) patients and to explore how…SRY as a potential therapeutic target for men with Parkinson’s Disease
Objective: Develop a potential disease-modifying gene therapy for men with Parkinson’s Disease Background: A hallmark symptom of PD is the loss of midbrain dopamine (DA)…Clinical and genetic analysis of psychosis in Parkinson’s disease
Objective: This study aimed to examine the association of seven selected polymorphisms of DRD2, ANKK1, COMT and DAT genes with Parkinson’s disease psychosis (PDP) onset.…Silencing of hypoxia-inducible factor 1 alpha provokes a neuroprotective response in a SH-SY5Y model of Parkinson’s Disease.
Objective: Our study aims to delineate the role of HIF1α in a SH-SY5Y model of Parkinson’s disease (PD) Background: Parkinson’s disease (PD) is one of…
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