Lysosomal storage disorder genes variants in Parkinson’s disease: a large cohort study in Chinese mainland population
Objective: In this study, we investigated the association between rare variants in lysosomal storage disorders (LSDs) genes and Parkinson’s disease in large Chinese mainland cohorts.…Gut microbiota and nutritional profiles of Parkinson’s disease patients.
Objective: We investigated the gut microbiome (GM) composition in association with various clinical features and nutritional data in a large cross-sectional Australian Parkinson’s disease (PD)…Motor cerebro-cerebellar networks breakdown among different subtypes of Parkinson’s disease
Objective: The aim of this study was to investigate functional alterations within motor circuits of the cerebro-cerebellar system in tremor-dominant (TD) and postural instability and…Impaired interhemispheric synchrony in Parkinson’s disease patients with impulse control disorders
Objective: Our objective was to probe the significant role of lateralization in the pathogenesis of ICD. Background: Impulse control disorders (ICD) in Parkinson’s disease (PD) might…Sex differences in brain and cognition in de novo PD patients
Objective: We aimed to investigate sex differences in brain atrophy and cognition in PD de novo patients through MRI subcortical volumetry and cortical thickness (CTh).…Motor symptom lateralization influences cortico-striatal functional connectivity in Parkinson’s disease
Objective: To evaluate the effect of lateralization on various cortico-striatal circuits through resting state functional MRI. Background: Striatum is unevenly impaired bilaterally in Parkinson’s disease.…Slow wave activity as a marker of levodopa induced dyskinesia
Objective: To assess the role of slow wave activity during slow wave sleep (SWS-SWA) as a marker of levodopa induced dyskinesia (LID) development in Parkinson's…Influence of Levodopa on Archimedes Spiral Drawings in Idiopathic Parkinson’s Disease
Objective: To study the effects of levodopa on Archimedes spiral drawings by idiopathic Parkinson’s Disease (PD) patients. Background: Handwriting difficulty can develop as an early…Mapping intrinsically photosensitive retinal ganglion cells (ipRGCs) dysfunction in patients with Parkinson disease using Chromatic pupilloperimetry
Objective: To characterize the focal intrinsic and extrinsic light responses in intrinsically photosensitive retinal ganglion cells (ipRGCs) at central and peripheral retina in patients with…Implementing Systematic Screening and a Treatment Algorithm for Depression in Parkinson’s Disease
Objective: Assess the feasibility and impact of systematic depression screening and management in movement disorders centers. Background: Depression is common in Parkinson’s disease (PD) and…
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