Homeostatic Improvement of Brain Bioenergetic Metabolism in Parkinson’s Disease: Results From A Phase 2 REPAIR-PD Clinical Trial With CNM-Au8
Objective: To determine the effects of the nanocatalytic drug, CNM-Au8, on brain energy metabolites in Parkinson’s Disease. Background: Converging lines of evidence are identifying brain…Application of the updated MDS criteria for prodromal Parkinson’s disease to a population-based 10-year study
Objective: We aimed to identify differences and analyze the potential added value of the updated Movement Disorders Society (MDS) research criteria for prodromal Parkinson’s disease…The Development of a Parkinson’s Disease Biomarker Inventory Dashboard
Objective: There is an urgent need for validated biofluid biomarkers in Parkinson’s disease (PD) drug development. Under the auspices of the Critical Path for Parkinson’s…EFFECT OF TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) ON LOCOMOTOR FUNCTION IN PATIENTS WITH PARKINSON’S DISEASE
Objective: Objectives Primary objective: To determine the effect of bilateral anodal transcranial direct current stimulation (tDCS) on locomotor function in patients with Parkinson’s disease immediately…Feasibility of Instituting Graduated High intensity Training (FIGHT-PD); Protocol for a non-contact boxing exercise study
Objective: 1. To determine the feasibility and logistics of conducting a non-contact boxing exercise program for PD patients. 2. To determine the tolerability of the…Adopting a low-cost multidisciplinary telemedicine approach for falls prevention in Parkinson´s Disease.
Objective: Healthcare services have been compromised during the COVID-19 pandemic, owing to limited access to multidisciplinary care. Our main aims are to describe the methods…Cuneiform Nucleus Deep Brain Stimulation for Freezing of Gait in Parkinson’s disease. Initial clinical report.
Objective: Here we report a first in human targeting of Cuneiform Nucleus (CnF) using MR tractography, observation of intraoperative stimulation patterns and stimulation precision benefits of…Celiac disease-related antibodies in Parkinson’s Disease patients: a case control study.
Objective: To compare anti-transglutaminase and antigliadin antibodies between Parkinson’s disease patients and healthy controls. A detailed gastrointestinal symptom investigation was studied and compared between patient…SB-0107, a drug repurposing opportunity identified through machine learning, shows the potential to treat Parkinson’s disease motor disability and levodopa-induced dyskinesia in rat and primate models
Objective: To characterize the effects of a computationally identified small molecule in rat and primate models of Parkinson’s disease-associated motor deficits and treatment-associated complications. Background:…Effects of low frequency repetitive transcranial stimulation over right dorsolateral prefrontal region on clinical symptoms and sleep structure of Parkinson’s disease Abstract
Objective: We aim to investigate the effects of low-frequency rTMS over the dorsolateral prefrontal cortex (DLPFC) on sleep and other symptoms in PD patients. Background:…
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