Parkinson’s disease patients may be at higher risk of Covid-19 mortality
Objective: To investigate the Covid-19 mortality in Parkinson’s disease (PD) patients. Background: PD patients may be at increased risk of Covid-19 mortality due to the…NMDA Receptor Antibodies and Neuropsychiatric Symptoms in Parkinson’s Disease
Objective: To quantify the frequency of NMDA receptor (NMDAR) antibodies (Abs) in Parkinson’s disease (PD) and characterise their relationship with the cognitive and neuropsychiatric symptoms.…Falls in Parkinson’s Disease: The Impact of Cognitive Performance
Objective: This study aimed to assess the incidence of falls in a population of PD patients and their clinical performance on cognitive assessment scales. Background:…GP2: training the next generation of Parkinson’s disease genetics researchers – wherever they are in the world
Objective: To establish a virtual ‘center of excellence’ with resources and expertise to serve the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org)…Familial Parkinson’s disease (PD) with anticipation phenomenon. Undescribed variant in the LRRK2 gene (c.4001G> A (p.Arg1334Gln))
Objective: We describe a family with 4 members affected by PD, carrying a new variant of the LRRK2 gen, with anticipation phenomenon in succeding generation.…Genotype-phenotype relations for GBA as a Parkinson’s disease risk factor gene: MDSGene Systematic Review
Objective: To provide a comprehensive and systematic review of genotype-phenotype associations of GBA variants for Parkinson’s disease (PD). Background: Biallelic pathogenic variants in the glucocerebrosidase gene (GBA) cause Gaucher disease (GD).…Impaired glucocerebrosidase transport to lysosomes in cultured macrophages derived from blood monocytic cells of patients with Parkinson’s disease associated with mutations in the GBA gene
Objective: To study the glucocerebrosidase (GCase) activity and translocation to lysosomes in cultured macrophages derived from patient blood monocytic cells (PBMC) of Parkinson's disease patients…Substantia nigra pars compacta integrity is associated with DRT-related motor symptom improvement in Parkinson’s disease
Objective: To study the correlation between substantia nigra white matter integrity and response of motor symptoms to dopamine replacement therapy (DRT) in Parkinson’s disease (PD).…Compensatory functional mechanisms of response inhibition in Parkinson’s Disease with impulse control disorders
Objective: To investigate response inhibition in Parkinson’s disease (PD) patients with impulse control disorders. Specifically, the neural underpinnings of two aspects of inhibition: proactive inhibition…Clinical correlates of Parkinson’s disease metabolic pattern: not only a diagnostic tool
Objective: To define and cross-validate the glucose metabolism abnormalities related to Parkinson's Disease (PD), and to analyze pattern relationship with clinical phenotype Background: In PD,…
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