Repetitive transcranial magnetic stimulation for hypokinetic dysarthria in PD enhances white matter integrity in the auditory-motor loop tract
Objective: To test effects of repetitive transcranial magnetic stimulation (rTMS) for hypokinetic dysarthria in PD on white matter integrity changes of the left anterior arcuate…Machine Learning and Instrumented Gait Analysis to Classify Subthalamic DBS States in Parkinson’s Disease
Objective: This study investigates whether gait features derived from an instrumented walk can predict specific treatment conditions (stimulation frequency and medication status) in a cohort…Longitudinal assessment of quality of life in early Parkinson’s disease: 5-year follow up study
Objective: To determine changes in HR-QoL in early PD patients during a 5-year follow up period. Background: There is limited evidence on longitudinal changes in…Factors that negatively impact the sexual function of women living with Parkinson’s disease
Objective: To investigate the impact of motor and non-motor alterations and couple adjustment on sexual function in women living with PD in Brazil. Background: Among…LRRK2 Inhibition by BIIB122: Trial designs for two efficacy and safety studies in Parkinson’s disease patients with and without LRRK2 mutations (Lighthouse and Luma)
Objective: Describe Luma and Lighthouse, two studies that investigate efficacy and safety of BIIB122, a LRRK2 inhibitor. Background: Increased LRRK2 kinase activity has been linked…Level of glial neurotrophic factor in the blood plasma depending on the duration of Parkinson’s disease
Objective: To study the level of glial neurotrophic factor in the blood plasma depending on the duration of PD. Background: Study of the biochemical aspects…RESPONDING TO COVID-19: THE “ALMEIDA-SANG EQUATION” TO PREDICT TOTAL DISEASE SEVERITY IN PARKINSON’S
Objective: To predict total disease severity in Parkinson’s disease (PD) for online assessments. Background: Assessment (and hence management) of PD has largely been affected by…Comparison of Antiparkinsonian Medication Initiation and Levodopa-Equivalent Daily Dose Across PPMI, STEADY-PD III, and SURE-PD3
Objective: To compare use of antiparkinsonian medications (APM) among early Parkinson disease (PD) patients across clinical study cohorts. Background: Initiation of APM is a key…Influence of onset of motor fluctuations on the effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations: findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the influence of onset of motor fluctuation (OMF) on the response to opicapone (OPC) treatment in patients with Parkinson’s disease…Effect of H. pylori Infection on L-DOPA Pharmacokinetics in Patients with Parkinson’s disease.
Objective: To evaluate whether Helicobactor pylori (H.pylori) infection affects the pharmacokinetics of L-DOPA in patients with Parkinson’s disease (PD). Background: H. pylori infects gastric mucosa…
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