The Vall d’Hebron Initiative for Parkinson (VHIP) cohort: a prospective, longitudinal and observational study enrolling de novo Parkinson’s disease (PD) patients and carriers of PD-linked mutations for biomarker and pathophysiology studies
Objective: To describe the study protocol of the Vall d’Hebron Initiative for Parkinson (VHIP) cohort, a prospective, longitudinal and observational cohort study aimed at deeply…The distinctive functional connectivity of the cholinergic nucleus basalis of Meynert in Parkinson’s disease across different motor subtypes
Objective: We aim to compare the state of cortical-NBM functional connectivity across healthy control (HC), PIGD-predominant PD (PIGD-PD), and tremor-dominant PD (TD-PD). Additionally, the correlation…The Correlation Analyses of Parkinson’s Disease with Serum Homocysteine, Folic Acid and Vitamin B12
Objective: To explore the associations of serum homocysteine (Hcy), folic acid (FA) and vitamin B12 (VitB12) levels with the severity of Parkinson's disease (PD), as…Turning during single and dual tasking in Parkinson’s Disease
Objective: To investigate turning kinematics and intersegmental coordination in single (ST) and dual tasking (DT) in Parkinson’s Disease (PD) patients. Background: Successful turning depends on…Language Impairment in Isolated Rapid Eye Movement Sleep Behavior Disorder and de-novo Parkinson’s disease
Objective: This study aimed to examine whether the language impairment is presented in isolated rapid eye movement sleep behavior disorder (iRBD) and early-stage Parkinson’s disease…Investigating inflammatory mechanisms in iPSC-derived LRRK2 microglia
Objective: To characterize microglial function and inflammatory mechanisms in LRRK2-associated Parkinson’s disease (PD). Background: PD is a neurodegenerative disease affecting primarily dopaminergic neurons of the…EFFECTS OF OPICAPONE IN PARKINSON DISEASE AS ASSESSED BY KINEMATIC TECHNIQUES
Objective: We aimed to objectively investigate the effects of Opicapone on bradykinesia in Parkinson's Disease (PD) by kinematic analysis. Background: By increasing L-dopa bioavailability, catechol-O-methyl…A second level neuropsychological battery for Parkinson’s Disease. Normative data from the Italian population.
Objective: The main purpose of this work is to propose modern Italian co-normed data for a battery of ten widely used neuropsychological tests for Parkinsons’…NODDI- based maps as potential marker for Parkinson’s Disease.
Objective: To assess the predictive power of Diffusion Kurtosis Imaging (DKI) parameters obtained from Neurite orientation dispersion and density imaging tool (NODDI) to differentiate between…Are Subjective Cognitive Complaints a predictor of future cognitive decline in Parkinson´s Disease? – A longitudinal study
Objective: We aim to determine whether subjective cognitive complaints (SCC) may predict the development of cognitive impairment in Parkinson´s Disease (PD) Background: Subjective cognitive complaints…
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