Mobile Brain / Body Imaging in early Parkinson’s Disease: the Twin Brain project
Objective: We aimed to setup a novel Mobile Brain / Body Imaging (MoBI) system and to perform a feasibility study for the future investigations of…Effects of theta burst transcranial ultrasound stimulation on motor cortex excitability in Parkinson’s disease.
Objective: Evaluate the neurophysiological and clinical effects of low-intensity transcranial ultrasound stimulation (TUS) of motor cortex (M1) in patients with Parkinson’s disease (PD). Background: TUS…Alterations of the Right Olfactory Orbitofrontal Cortex and olfactory impairment in Parkinson’s Disease
Objective: To explore the potential role of the right olfactory orbitofrontal cortex in olfactory dysfunction (OD) in Parkinson’s Disease (PD). Background: The orbitofrontal cortex (OFC)…Determination of metabotropic glutamate 2 receptor distribution with [3H]-LY-341,495 in hemi-parkinsonian rats with L-DOPA-induced dyskinesia
Objective: To determine the distribution and density of metabotropic glutamate 2 (mGlu2) receptors in the motor loop of the basal ganglia in 6-hydroxydopamine (6-OHDA)-lesioned rats…Prediction of freezing of gait in Parkinson’s disease based on wearable sensors
Objective: The purpose of this study was to introduce an autoregressive predictive model to improve the accuracy for freezing of gait (FOG) prediction. Background: Parkinson’s…The role of RNA-carrying exosomes in synaptic physiology and in synucleinopathies
Objective: Our goals were: (i) to characterize the molecular mechanisms associated with the transfer of miRNAs from astrocytes to neuronal synapses via exosomes in transgenic…Feasibility and efficacy of a multidisciplinary telemedicine intervention program to reduce falls and gait impairment in Parkinson’s disease (NCT04694443).
Objective: To evaluate the feasibility and effectiveness of a multidisciplinary telemedicine intervention program to reduce falls and to improve quality of life (QoL) in patients…The crucial role of the visual system on the PISA syndrome in Parkinson’s disease
Objective: Patients with Parkinson's disease (PD) are significantly disturbed in their daily life when accompanied by the PISA syndrome (PS) of lateral bending. Background: We…Clinical practice feasibility of a wearable appcessory for quantitative evaluation of motor symptoms in Parkinson’s disease
Objective: This clinical study aims to evaluate the feasibility of a novel wearable system to quantify and monitor Parkinson’s disease (PD) motor symptoms (MS). In…Genetic subtypes of Parkinson’s disease in a Colorado clinic
Objective: The objective of this study is to investigate the natural history of genetic subtypes of Parkinson’s disease (PD) and characterize the genetic architecture of…
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