Determination of metabotropic glutamate 2 receptor distribution with [3H]-LY-341,495 in hemi-parkinsonian rats with L-DOPA-induced dyskinesia
Objective: To determine the distribution and density of metabotropic glutamate 2 (mGlu2) receptors in the motor loop of the basal ganglia in 6-hydroxydopamine (6-OHDA)-lesioned rats…Prediction of freezing of gait in Parkinson’s disease based on wearable sensors
Objective: The purpose of this study was to introduce an autoregressive predictive model to improve the accuracy for freezing of gait (FOG) prediction. Background: Parkinson’s…The role of RNA-carrying exosomes in synaptic physiology and in synucleinopathies
Objective: Our goals were: (i) to characterize the molecular mechanisms associated with the transfer of miRNAs from astrocytes to neuronal synapses via exosomes in transgenic…Feasibility and efficacy of a multidisciplinary telemedicine intervention program to reduce falls and gait impairment in Parkinson’s disease (NCT04694443).
Objective: To evaluate the feasibility and effectiveness of a multidisciplinary telemedicine intervention program to reduce falls and to improve quality of life (QoL) in patients…The crucial role of the visual system on the PISA syndrome in Parkinson’s disease
Objective: Patients with Parkinson's disease (PD) are significantly disturbed in their daily life when accompanied by the PISA syndrome (PS) of lateral bending. Background: We…Clinical practice feasibility of a wearable appcessory for quantitative evaluation of motor symptoms in Parkinson’s disease
Objective: This clinical study aims to evaluate the feasibility of a novel wearable system to quantify and monitor Parkinson’s disease (PD) motor symptoms (MS). In…Genetic subtypes of Parkinson’s disease in a Colorado clinic
Objective: The objective of this study is to investigate the natural history of genetic subtypes of Parkinson’s disease (PD) and characterize the genetic architecture of…Development and preliminary results of a new picture-based self-rating tool for neuropsychiatric syndromes in Parkinson’s disease
Objective: To develop a picture-based, non-verbal screening tool to detect neuropsychiatric syndromes (NPS), including depression, anxiety, apathy, fatigue, mania, impulse control disorder (ICD), sleeping problems,…SARS-CoV-2 infection exacerbates the cellular pathology in Parkinson’s disease progression
Objective: This study can provide an important insight for identification and prediction of long term neurological sequelae of SARS-CoV-2 infection and proper clinical management the…Stability of basal ganglia beta band power distribution during continuous deep brain stimulation in Parkinson’s disease: analysis of sub-cohort from the ADAPT-PD trial
Objective: To assess the stability of the daily distribution of peak subthalamic nucleus (STN) and globus pallidus internus (GPi) beta band power during continuous deep…
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