Transcutaneous auricular vagal nerve stimulation has frequency depended propensity to improve gait in Parkinson’s disease – a pilot study
Objective: We used wearable inertion motion sensors (WMS) to compare the acute effects of transcutaneous auricular vagal stimulation (taVNS) at 100Hz (taVNS100), 25Hz (taVNS25), and…IncobotulinumtoxinA to treat sialorrhea in Parkinson’s disease: a real-life study
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea (10 injection cycles (IC) into…Administration of the mGlu2 positive allosteric modulator BINA as monotherapy improves parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effect of selective metabotropic glutamate type 2 (mGlu2) receptor activation on parkinsonism as monotherapy in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset compared to…Neural correlates of Parkinson’s disease dysgraphia
Objective: This study aims to evaluate the functional correlates of Parkinson’s disease (PD) dysgraphia from coupled fMRI and kinematic recordings. Background: Beyond the abnormal reduction…Gait Characteristics from Daily Life Increase Ability to Predict Future Falls in People with Parkinson’s Disease
Objective: We investigated if digital measures of different aspects of gait (walking and turning) from a week of daily activities increase discriminative ability to predict…Gait analysis using Wearable Sensors: different gait metrics can differentiate Parkinson’s Disease Patients from Healthy Controls and Parkinson’s Disease patients in different medication status
Objective: To identify which gait metrics better distinguish PD-OFF from PD Best-ON and PD from HC, using a dimensionality-reduction method Background: Objective gait analysis using…Decrease of striatal activity during the execution of a everyday-life motor habits in early Parkinson’s disease.
Objective: The aim of this study was to investigate the influence of dopaminergic cell loss on motor habitual behaviour, by comparison between newly diagnosed Parkinson’s…Impulse control disorder following bilateral pallidothalamic tract focused ultrasound: a case report
Objective: Description of a case of ICD following non-contemporaneous bilateral pallidothalamic focused ultrasound tractotomy. Background: Impulsive and compulsive behaviours in PD are hypothesized to largely…A Randomized, Wait-List Controlled Trial of the Feasibility and Efficacy of Small Group Online-based Cognitive Behavioral Therapy for Anxiety in Parkinson’s Disease
Objective: To investigate the feasibility and efficacy of online-based Cognitive Behavioral Therapy (CBT) for anxiety in Parkinson's disease (PD). Background: Anxiety symptoms in Parkinson's disease…Understanding the continuing educational needs of US clinicians managing OFF episodes in Parkinson’s disease
Objective: This study sought to understand the continuing medical education (CME) needs of US-practicing neurologists (NEUROs) and neurology advanced practice providers (APPs) in managing patients with Parkinson’s Disease (PD) experiencing…
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