A dose-response study of the effect of the mGlu2/3 orthosteric antagonist LY-341,495 on the anti-dyskinetic and anti-psychotic effect of the mGlu2 positive allosteric modulator LY-487,379 in the MPTP-lesioned marmoset
Objective: To assess the effects of different doses of the metabotropic glutamate 2 and 3 (mGlu2/3) orthosteric antagonist (OA) LY-341,495 on the anti-dyskinetic and anti-psychotic…Action verb use in PD: A challenge to the embodied cognition hypothesis?
Objective: To characterize action verb production in Parkinson's disease (PD) during a picture description task, and evaluate associations with motor and cognitive function. Background: The…Drivers of burden over time in caregivers of patients with Parkinson’s disease and related disorders: Findings from a community-based clinical trial of outpatient palliative care
Objective: To identify predictors of accelerated caregiver burden in patient-caregiver dyads of people with Parkinson’s disease and related disorders (PDRD). Background: PDRD are characterized by…Mindfulness based program for newly diagnosed Parkinson’s patients.
Objective: To investigate the impact of 8-week course of Mindfulness based intervention program on motor and or non-motor symptoms of PD assessed by improvement in…Relationship between falls and motor state in Parkinson’s disease patients with motor fluctuations
Objective: To elucidate in which motor state Parkinson’s disease (PD) patients with motor fluctuations fall. Background: Recurrent falls are a disabling feature of PD and…Social Withdrawal in Parkinson’s Disease: A Scoping Review
Objective: We conducted a scoping review to understand the nature and impacts of social withdrawal in PD and identify evidence gaps. Background: Social withdrawal has…Effect of clinical levodopa medication cycle on subthalamic beta band power during therapeutic deep brain stimulation in Parkinson’s disease
Objective: To characterize the effect of levodopa medication cycle on subthalamic nucleus (STN) local field potential (LFP) beta-band power in Parkinson’s disease (PD) in the…Parkinson’s patient insights, knowledge and experience of treatment – results from a multicountry survey
Objective: To understand the perceptions and knowledge that people with Parkinson’s disease (PD) have about their treatment, available options for advanced PD, and to determine…Gray matter volumetry, cortical thickness and cognitive performance in treated Parkinson’s disease with REM sleep behavior disorder symptomatology
Objective: To explore MRI subcortical and cortical gray matter measures, as well as cognitive performance, in treated PD patients with REM sleep behavior disorder (RBD)…Subcortical Atrophy and Fall Risk in Parkinson’s Disease
Objective: To evaluate the relationship between various measures of subcortical atrophy with fall risk in PD. Background: Falls occur in nearly 70% of people with…
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