Sub-cellular alterations in MPTP-induced in-vivo and in-vitro systems and Non-MPTP human Parkinsonian skin biopsies: Verifying the sequelae of differential toxicity
Objective: To evaluate the possible temporal hierarchy of sub-cellular organellar degeneration in experimental models of Parkinson’s disease (PD), using MPTP/MPP+ Background: Higher prevalence of PD in…Genetic study of early-onset Parkinson’s disease in the Malaysian population
Objective: This study aimed to investigate the genetic architecture of EOPD in a multi-ethnic Malaysian cohort. Background: About 5-10% of Parkinson’s disease (PD) cases are…Sleep quality in GBA, LRRK2 and idiopathic Parkinson disease
Objective: To describe sleep characteristics and quality in GBA, LRRK2 and non-genetic idiopathic Parkinson disease. Background: Sleep disturbances are one of the most common non-motor…Correlation between hemoglobin level and disease severity in patients with Parkinson’s disease
Objective: Objective of this study was to investigate the potential correlation between hemoglobin levels and Parkinson's disease (PD) severity, and to compare them with a…Piloting the Cats-and-Dogs tool as a culture-fair test for sensory processing impairment in Parkinson’s disease
Objective: This pilot explored the feasibility and culture-fairness of a psychophysical visuoperceptual test for Parkinson’s disease (PD) in a multicultural population in East London. Background:…Recruitment of Parkinson’s disease patients with mild-to-moderate anxiety into a randomized controlled trial: Experience of a large Canadian tertiary movement disorders clinic
Objective: To report our experience of recruiting Parkinson’s disease (PD) patients with mild-to-moderate anxiety into a randomized controlled trial. Background: Anxiety is a common non-motor…Inferring Rigidity Scores in MDS-UPDRS Motor Assessment from Other Items
Objective: This study aimed to explore the possibility of inferring rigidity scores in MDS-UPDRS assessments from other items to enhance the accuracy of clinical evaluations…Current practices for ‘timing’ of physical therapy in Parkinson’s Disease: ‘Burst vs. Spaced’
Objective: To assess current practices for timing of physical therapy (PT) in Parkinson’s disease (PD). Background: Most persons with Parkinson disease (PD) face increasing mobility…Premenstrual worsening of UPDRS motor scale in women affected by Parkinson’s Disease
Objective: The role of estrogen in dopaminergic pathways and the premenstrual worsening of parkinsonian symptoms. Background: Female sex hormones, during the menstrual cycle, could influence…Characterization of at-home sleep macrostructure in Parkinson disease using a wearable sleep monitoring device
Objective: Determine the viability of a wearable reduced montage EEG device to record sleep in a population of patients with Parkinson disease (PD). Background: Sleep…
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