Identifying Differential DNA Methylation Pathways in Parkinson’s Disease and REM Sleep Behavior Disorder
Objective: To investigate differential methylation patterns of cell-free DNA (cfDNA) between Parkinson’s Disease (PD), REM Sleep Behavior Disorder (RBD), and Healthy Control (HC) groups. Background:…Studying the Influence of Genetic Variations on Functional Performance in Parkinson’s Disease
Objective: To evaluate whether individuals with one of the seven most common genetic variants associated with Parkinson’s Disease (PD) exhibit differences in physical function performance…Revealing Novel Genetic Contributors to Parkinson’s Disease in a Chinese Cohort: An Elaborate Examination within the CPD10KGP
Objective: This study employs next-generation sequencing (NGS) and long-read sequencing data (LRS) in Chinese AR-PD families to uncover novel genes, enhancing our genetic comprehension of PD. Background:…Management of peri-lead cyst after Deep Brain Stimulation surgery: Review of literature and an illustrative case report
Objective: Identification and management of an unusual complication following Deep Brain Stimulation surgery (DBS). Background: DBS is a well established treatment modality that has found…Low Frequency Directional Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-Resistant Freezing of Gait: Six-Month Outcomes.
Objective: This is a prospective, open-label, single-arm study to assess safety and efficacy of cuneiform(CnF) deep brain stimulation(DBS) in Parkinson's disease(PD) patients with levodopa-refractory freezing…Intraoperative deep brain stimulation intrinsic lead migration
Objective: To characterize the intrinsic deep brain stimulation (DBS) lead migration as it relates to different deep brain targets. Background: Effective DBS relies on careful…Distinguishing DBS and Non-DBS Parkinson’s Patients Using Recurrence Plots and Vision Transformers
Objective: To introduce an innovative method for distinguishing gait patterns in Parkinson’s Disease (PD) patients with medical or surgical treatment and healthy controls, by exploiting…Prodromal Clinical Markers of Parkinson disease in patients with Gaucher disease and their parents
Objective: To determine the presence of prodromal markers of Parkinson’s disease (PD) in Gaucher disease (GD) patients and their parents. Background: GBA gene mutation is…The Effects of Non-pharmacological Treatments for Parkinson’s Disease Sleep Disorders:A Systematic Review and Meta-Analysis
Objective: This meta-analysis aimed to assess the clinical efficacy of various non-pharmacological therapies for PD sleep disorders (PDSD) to inform treatment strategies. Background: Sleep disorders…Sex variations in non-motor symptoms (pain, fatigue, and nausea) in Parkinson’s disease patients: An analysis from the Mexican Parkinson’s Research Network
Objective: To compare pain, fatigue and nausea variables between sexes to see if there is a significant difference. Background: Patients with PD present motor and…
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