Early functional disruption in body-first compared to brain-first Parkinson’s disease
Objective: To analyze differences in functional connectivity (FC) between Parkinson’s disease (PD) patients with and without premotor REM behavior disorder (pRBD), by means of high-density…Depression in Parkinson’s disease is associated with subcortical neurodegeneration and increased risk of all-cause mortality and dementia
Objective: To evaluate the temporality, neuroanatomical correlates and prognostic significance of depression in PD using a large population cohort. Background: Depression may be an important…Evaluation of possible pre-motor symptoms of Parkinson’s disease in a GBA-mutation positive cohort, as well as Gaucher disease patients.
Objective: To clinically evaluate a cohort of healthy glucocerebrosidase (GBA) mutation carriers in search of early biomarkers for neurodegeneration that may be prodromal features of…IncobotulinumtoxinA to treat sialorrhea in Parkinson’s disease: a real-life study: 4-year interim results
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea. Background: Sialorrhea is frequently a…Bilateral staged MRI-guided focused ultrasound subthalamotomy for Parkinson’s disease
Objective: To assess the feasibility and safety of bilateral staged focused ultrasound subthalamotomy(FUS-STN) for Parkinson's disease(PD). Background: Unilateral FUS-STN for PD improves contralateral motor features…Can the Ohm’s law predict the amplitude of neurostimulation when adapting systems in deep brain stimulation?
Objective: Review and analysis of clinical and neurostimulation parameters in patients with replacement of constant-voltage non-rechargeable implantable pulse generator (CV-nrIPG) by constant-current rechargeable IPG (CC-rIPG)…Dry Cleaning Chemicals and Parkinson’s Disease
Objective: To characterize health outcomes of attorneys potentially exposed to dry cleaning chemicals. Background: Trichloroethylene (TCE), a chlorinated solvent used in dry cleaning and degreasing,…Effect of Deep Brain Stimulation on the Motor Profile of Parkinson’s Disease in Egypt; A Developing Country Experience
Objective: To identify the effect of DBS of bilateral STN or bilateral GPi on different motor parameters of PD Background: Deep brain stimulation (DBS) of…Suicidal ideation and suicide risk in Parkinson’s disease
Objective: To examine the prevalence of suicidal ideation and suicide risk in patients with Parkinson’s disease (PD) and to assess the relationship between suicidal ideation…Sex differences in motor response to levodopa in early Parkinson’s disease
Objective: To evaluate differences between males and females in trajectory of motor response to levodopa in early Parkinson’s disease (PD). Background: Previous research has shown…
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