The relationship of non-motor symptoms in Parkinson’s disease
Objective: Evaluation of non-motor symptoms in patients with Parkinson's disease, evaluation of the relationship of autonomic and neuropsychiatric disorders. Background: This work included a comprehensive…Cerebro-cerebellar motor networks in clinical subtypes of Parkinson’s disease
Objective: This study investigated functional alterations within the cerebro-cerebellar system in tremor-dominant (TD) and postural-instability-and-gait-disorder (PIGD) subtypes of Parkinson’s disease (PD) using stepwise functional connectivity…The reasons for referral to a Parkinson’s Clinical Psychology service
Objective: To understand the reasons for referral to a Parkinson's Clinical Psychology service. Background: In recent times, the psychological impact of Parkinson’s Disease has become…Apomorphine Sublingual Film Versus Subcutaneous Apomorphine in the Treatment of OFF Episodes in Parkinson’s Disease: Results From an Assessment of Patient Satisfaction
Objective: Evaluate treatment satisfaction with apomorphine sublingual film (SL-APO) vs subcutaneous apomorphine (SC-APO) for the treatment of OFF episodes in patients with Parkinson’s disease (PD).…Antidyskinetic Effects of CaV1.3 Calcium Channel Gene Silencing in Aged Male and Female Parkinsonian Macaques
Objective: To determine whether striatal CaV1.3 gene silencing ameliorates levodopa-induced dyskinesias (LID) in the preclinical gold-standard non-human primate (NHP) model without altering levodopa’s antiparkinsonian benefit.…Impact on non-motor symptoms, cognition, and QoL after 1-year of DBS for Parkinson’s Disease: An interim report from the ADROIT NAPA sub-study
Objective: To present the impact on cognition, quality of life, and non-motor symptoms after 1-year of DBS for Parkinson’s Disease through the ADROIT post-market study.…Transcutaneous auricular vagal nerve stimulation has frequency depended propensity to improve gait in Parkinson’s disease – a pilot study
Objective: We used wearable inertion motion sensors (WMS) to compare the acute effects of transcutaneous auricular vagal stimulation (taVNS) at 100Hz (taVNS100), 25Hz (taVNS25), and…IncobotulinumtoxinA to treat sialorrhea in Parkinson’s disease: a real-life study
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea (10 injection cycles (IC) into…Administration of the mGlu2 positive allosteric modulator BINA as monotherapy improves parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effect of selective metabotropic glutamate type 2 (mGlu2) receptor activation on parkinsonism as monotherapy in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset compared to…Neural correlates of Parkinson’s disease dysgraphia
Objective: This study aims to evaluate the functional correlates of Parkinson’s disease (PD) dysgraphia from coupled fMRI and kinematic recordings. Background: Beyond the abnormal reduction…
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