Chronic administration of bitopertin, a GlyT1 inhibitor, in the dyskinetic 6-OHDA-lesioned rat model of Parkinson’s disease
Objective: To evaluate if, upon chronic administration, tolerance to the anti-dyskinetic effect of the glycine transporter 1 (GlyT1) inhibitor bitopertin, would develop, in the 6-hydroxydopamine…Differences between two cognitive assessment instruments used in Parkinson’s disease in Kyrgyzstan
Objective: The aim of this study was to determine differences between Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) in PD patients from Kyrgyzstan.…Fatigue at different stages of parkinson’s disease
Objective: study fatigue as a key non-motor symptom of parkinson's disease Background: Fatigue in PD refers to a state of fatigue, lack of energy, a…Cognitive-motor tests markedly increase the diagnostic rate of “On-meds” freezing of gait in Parkinson’s disease during clinical visits
Objective: To develop a testing and recording system that can reliably increase the rate of diagnosing freezing of gait (FOG) in patients living with Parkinson’s…Common mistakes in the MoCA test in patients with Parkinson’s Disease in Kyrgyzstan
Objective: The aim of the study is to identify common mistakes in MoCA in patients with Parkinson’s disease (PD) in Kyrgyzstan. Background: Cognitive impairment is…Changes in anticholinergic burden in patients with Parkinson’s disease (PD) after bilateral deep brain stimulation (DBS) of the globus pallidus (GP) and subthalamic nucleus (STN)
Objective: To evaluate the effect of GP and STN DBS upon anticholinergic medication burden in patients with PD. Background: Medications with anticholinergic effects are commonly…The level of glial neurotrophic factor in blood plasma depending on the stage of Parkinson’s disease
Objective: To study the level of glial neurotrophic disease in blood plasma in patients with Parkinson's disease (PD) depending on the stage Background: Parkinson's disease…Deep learning applied to retinal OCT images to differentiate Parkinson’s disease patients from healthy controls
Objective: This study aims to investigate the capability of artificial intelligence, more precisely deep convolutional neural networks (CNN), to automatically classify between healthy controls (HC)…A One-year follow-up study of effects of voltage/frequency Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) adjustments on speech intelligibility in Parkinson’s Disease (PD)
Objective: To assess the relationship between along-1-year stimulation voltage(V)/frequency(F) adjustments and speech intelligibility (SI) in PD patients treated with STN-DBS. Background: Low V/F stimulation improves…New-onset gait problems after bilateral STN-DBS for Parkinson’s disease: A systematic review
Objective: In this systematic review, we provide an overview of an underrecognized, but common side effect related to deep brain stimulation of the subthalamic nucleus…
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