Cognitive and Functional Trajectories in Prediagnostic Parkinson’s Disease
Objective: To describe prediagnostic cognitive and functional trajectories in Parkinson’s Disease (PD). Background: Cognitive and functional decline is typically considered a late manifestation of PD.…Epidemiologic And Clinical Features Of Psychiatric Disorders In Patients With Parkinson’s Disease – A Retrospective Cohort Study
Objective: We aimed to assess the average duration of Parkinson's disease at the time patient was diagnosed with specific neuropsychiatric disturbance, to study their prevalence…Long-term efficacy of unilateral high-intensity focused ultrasound subthalamotomy for Parkinson’s Disease
Objective: To explore the long-term safety and efficacy of focused ultrasound subthalamotomy (FUS-STN). Background: Unilateral MRI-guided high-intensity FUS-STN improves motor signs of Parkinson’s disease (PD) [1]…Caregiver burden and quality of life in late stage Parkinson’s disease
Objective: To describe and assess factors associated with informal caregiver quality of life (QoL) in late stage Parkinson’s disease (PD). Background: In the late stage…Effect of levodopa-carbidopa intestinal gel on lower urinary tract symptoms in Parkinson’s disease: an Urodynamic study
Objective: Here we report urodynamic results before and six months after LCIG treatment in PD patients suffering from LUTS. Background: Dopaminergic transmission plays a key…Safety of opicapone after 5 years of post-marketing experience worldwide
Objective: To review the safety data of opicapone (OPC) after five years of marketing experience worldwide Background: OPC is a once-daily catechol-O-methyltransferase (COMT) inhibitor proven…The REONPARK (REgistry of the use of COMT-inhibitors in the maNagement of patients with PARKinson’s disease in Spain who present early motor fluctuations) study: rationale and design of a national, multicentre and prospective study
Objective: To describe the real-world use of catechol-O-methyltransferase (COMT) inhibitors add on to levodopa/dopa decarboxylase inhibitor (DDCI) in patients with Parkinson’s disease (PD) suffering from…Continuous wavelet transforms to improve the accuracy of motor assessments of Parkinson’s disease
Objective: We sought to develop a protocol to utilize continuous wavelet transforms (CWTs) to rate the severity of movements to obtain optimal classifications of PD.…An Ecologic Study of Aqueous Lead Exposure and Parkinson’s Disease
Objective: Examine the potential role of lead in water as a risk factor for PD. Background: Studying disease rates in different locations is an established…Multidimensional phenotyping of human stem cell-derived midbrain dopaminergic neurons from a SNCA triplication carrier for drug screening applications
Objective: We hypothesized that combining multiple Parkinson's disease (PD) relevant cellular phenotypes will increase the accuracy, stability, and usability of human midbrain dopaminergic (mDA) neuronal…
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