Is GPI DBS as effective to STN DBS for tremor control in Parkinson’s disease?
Objective: To compare the benefits of GPI and STN DBS on tremor in Parkinson’s disease (PD). Background: DBS is a highly effective surgical therapy for…Do differences in risk aversion and perceived social support contribute to gender disparities in deep brain stimulation utilization in Parkinson’s disease
Objective: To examine gender differences in risk tolerance in Parkinson’s disease and to determine factors associated with risk tolerance. Background: Deep brain stimulation (DBS) is…Viability and Accuracy of Visual Estimation in Determining Directional Deep Brain Stimulation Lead Orientation
Objective: To assess the viability and accuracy of visual estimation in determining directional deep brain stimulation (DBS) lead orientation. Background: Directional DBS leads show large…The Current State of Wearable Device Use in Parkinson’s Disease (A Survey of Individuals with Parkinson’s and Specialist Clinicians)
Objective: To develop a better understanding of the current use of consumer and medical wearable monitoring devices in the clinical management of PD and to…Wearable Device for Real-Time Prevention of Freezing-of-Gait in Parkinson’s Disease
Objective: In our previous work, we developed machine learning models to predict and detect freezing-of-gait (FOG) [1]. In this study, we aimed to use those…SMaRT-PD: A Clinical Decision Support System for the Management of Parkinson’s Disease
Objective: To optimise the accuracy of a clinical decision support system (CDSS) to support Self-Management, Remote monitoring and Timely review in Parkinson’s Disease (SMaRT-PD). Background:…A Device Agnostic Pipeline for Gait Detection and Assessment in Free-living and Clinical Environments
Objective: To provide a framework for a device agnostic gait analytics pipeline for standardizing and improving quantitative gait analysis using wearable sensors. Background: Gait impairments…GBA1 deficiency differentially affects endolysosomal trafficking in neurons and astrocytes
Objective: To characterize how GBA1 deficiency alters endolysosomal trafficking in astrocytes versus neurons. Background: Mutations in the gene glucosidase, beta acid 1 (GBA1) not only increase risk…PD GENEration: a genetic analysis beyond the classical 7 Parkinson’s disease genes
Objective: To expand the analysis of whole-exome sequencing (WES) data from patients with Parkinson’s Disease (PD) from the PD GENEration cohort. We looked for variants…Assessing Genome-wide Genetic Risk for Parkinson’s Disease in European Sub-Populations Across the Global Parkinson’s Genetics Program and National Biobanks
Objective: To assess genome-wide genetic risk for Parkinson’s disease (PD) within and across genetically determined European ancestries (European, Ashkenazi Jewish, and Finnish) from the Global…
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