CSF Cadaverine and Other Polyamines as Biomarkers of Parkinson’s Disease: A PPMI Metabolomics Analysis
Objective: To identify novel biomarkers of Parkinson’s disease (PD) in Parkinson's Progression Markers Initiative (PPMI) cerebrospinal fluid (CSF) samples. Background: Altered polyamine levels in plasma…Immune cell changes in early Dementia with Lewy Bodies
Objective: To examine if immune cell changes are present in early stages of Dementia with Lewy Bodies (DLB). Background: Evidence for inflammation in synucleinopathies has…Reliability and Validity of In-home Tele-Neuropsychological Testing in Patients with Parkinson’s Disease: A Randomized Trial
Objective: To assess the reliability and diagnostic validity of in-home tele-neuropsychological testing (in-home tele-npt) in individuals with Parkinson’s disease (PD). Background: Neuropsychological testing is inaccessible…Baseline cerebrospinal levels of p-tau and amyloid beta and striatal dopamine transporter binding predict mild cognitive impairment and dementia diagnosis in Parkinson’s disease
Objective: To assess whether baseline measurements of neuroimaging and biofluid-based biomarkers predict diagnosis of mild cognitive impairment (MCI) and dementia at 5-year follow-up in early…Atypical Psychosis in Parkinson Disease: A Retrospective Study on 24-Hour Continuous Subcutaneous Infusion Foslevodopa/Foscarbidopa Therapy
Objective: This study aims to identify clinical predictors of continuous subcutaneous infusion (CSCI)-induced psychosis to understand its potential mechanisms and evaluate predictive measures for its…Demographic Features, QTc Interval and Psychosis in Military Veterans with Parkinson’s disease (PD)
Objective: To compare certain key demographic features and QTc intervals in groups of PD military Veterans with and without psychosis. Background: Psychosis is a disabling…The relationship between synuclein-related biomarkers and people with upper-respiratory causes of hyposmia or persistent hyposmia
Objective: To determine how smell-testing can enrich screening for individuals with biomarkers related to neuronal alpha-synucleinopathy-related neurodegeneration (NSD). Background: Loss of sense of smell is the…Knowledge, Perception and Access to Care for Parkinson’s Disease in Two Selected Local Government Areas in Lagos State, Southwestern Nigeria.
Objective: We aimed to study the knowledge and perception of Parkinson’s disease (PD) and awareness of available care options for PD diagnosis in our population.…Real-life experience with continuous subcutaneous foslevodopa/foscarbidopa infusion in advanced stage of Parkinson’s disease at Villa Margherita
Objective: We present the results of our case series with continuous subcutaneous infusion (CSCI) produodopa in 2024, focusing on tolerability and efficacy, in line with…Nasal septum deviation correlates with asymmetry in Parkinson’s disease
Objective: To assesse whether asymmetry in the nasal cavity is related to dopaminergic dysfunction asymmetry in PD patients Background: Asymmetry in motor dysfunction and associated dopaminergic…
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