Predictive model for Identification of device-aided therapy (DAT) Candidates in Parkinson´s Disease (DELIST-PD Study)
Objective: To develop a classification algorithm based on machine learning to identify candidates for device-aided therapy among patients with Parkinson's disease (PD). Background: DATs (deep…Oculomotor parameters measured during free viewing of video differentiate Parkinson’s disease from progressive supranuclear palsy
Objective: Characterize oculomotor phenotypes comprised of saccade, pupil, and blink behaviour for progressive supranuclear palsy (PSP) and Parkinson’s disease (PD) with differing degrees of cognitive…Can radiofrequency lesion be better than DBS?
Objective: Pallidotomy represents a viable alternative for Parkinson disease(PD) symptoms treatment and has several important advantages, including a decreased need for access to specialists and clinical follow-up, improved affordability, and a lower infection risk, producing high long-term success rates and low morbidity rates. Background: Pallidotomy is recognized as effective for treating the symptoms of Parkinson's disease. Sometimes, radiofrequency may…Comparing the outcome under General Anaesthesia (GA) and Monitored Anesthesia Care (MAC) of Subthalamic Nucleus (STN) – Deep Brain Stimulation (DBS) Surgery for Parkinson’s Disease (PD) in Hong Kong – A single center experience
Objective: To evaluate any difference in the clinical outcome under GA and MAC of STN DBS surgery Background: Traditionally, DBS surgery is performed under MAC…Levodopa-induced orthostatic hypotension in a large cohort of patients with Parkinson’s disease undergoing an acute levodopa challenge test
Objective: We aimed to investigate the frequency and associated risk factors for Levodopa-induced orthostatic hypotension (OH) in a large cohort of PD patients underwent acute…Rasagiline in Chinese patients with early-stage parkinson’s disease: a randomized, double-blind, placebo-controlled, delayed-start trial
Objective: Objective: This randomized, double-blind, placebo-controlled, delayed-start trial aimed to investigate the efficacy in symptom improvement and disease-modifying effect of rasagiline for Chinese patients with…Diplopia (Double vision) in Parkinson’s disease patients: prevalence and nonmotor effect
Objective: To assess the prevalence of diplopia in Parkinson’s disease (PD) patients and the correlation of diplopia with visual hallucinations, cognitive dysfunction and motor performance.…Fluorescence-lifetime ophthalmoscopy findings in Parkinson’s disease patients with visual disturbances
Objective: We identified fluorescence-lifetime ophthalmoscopy changes in Parkinson’s disease (PD) patients experiencing visual disturbances. Background: Fluorescence-lifetime ophthalmoscopy (FLIO), a novel in vivo imaging method generating…Targeting autophagy to identify novel modulators of Parkinson’s disease using midbrain organoids
Objective: Natural compound libraries are a great source of new chemical molecules that could restore the altered phenotypes in patient derived cells. The objective of…Gray matter volume changes in occipital and temporal visual brain region are associated with freezing of gait in Parkinson’s
Objective: This study aimed to investigate the association of changed gray matter volume(GMV)with Freezing of gait(FOG) in Parkinson’s disease(PD). Background: FOG is a characteristic gait…
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