An investigation of early changes in the brain due to mild cognitive impairment in Parkinson’s disease
Objective: To identify baseline structural brain differences between individuals with Parkinson's disease (PD) who go on to develop mild cognitive impairment (PD-MCI) and those who…Towards smart glasses for improved care of individuals with Parkinson’s disease
Objective: To evaluate the applicability of sensor-enabled smart glasses for remote tracking of symptoms related to Parkinson’s disease Background: Diagnosis and monitoring of PD by…Metabolic modulation of mitochondrial DNA release in cellular models of Parkin-associated Parkinson’s disease
Objective: Our objective in this study was to elucidate the mechanisms underlying the release of mtDNA in cellular models of Parkin-associated Parkinson’s disease and to…Effects of combined subthalamic and dorsolateral nigral deep brain stimulation on gait performance in Parkinson’s Disease
Objective: To investigate short-term effects of combined deep brain stimulation (DBS) of the substantia nigra pars reticulata (SNr) and subthalamic nucleus (STN) on gait performance,…Testing gene-environment interaction in Parkinson’s disease (PD) using whole-genome sequencing of pesticide-exposed cohorts.
Objective: To identify interactions of specific pesticides with genetic loci to find causal variants for PD using gene burden analysis (BA). Background: Pesticide exposure is…Subtyping Parkinson’s disease: Quality of life changes after subthalamic stimulation depend on nonmotor and motor symptoms
Objective: To investigate if patients with Parkinson’s disease (PD) undergoing subthalamic stimulation (STN-DBS) can be clustered in different subtypes based on demographic, motor and non-motor…Neuroimaging correlates of postural instability in motor subtypes of Parkinson’s disease
Objective: In this study, we aimed to identify the brain structures associated with postural instability (PI) in Parkinson’s disease (PD) subtypes using different MRI approaches. Background:…Potential genetic link between type I diabetes and Parkinson’s disease.
Objective: To examine whether type 1 diabetes (T1D) is genetically or causally associated with Parkinson’s disease (PD). Background: Previous epidemiological and mendelian randomization studies demonstrated…Blood derived α-synuclein seeding in the course of Parkinson’s Disease
Objective: To identify seeding capacities of soluble α-synuclein (α-syn) conformers derived from neuronal extracellular vesicles (NEs) from Parkinson´s disease (PD) patients with different disease durations…Hesperidin ameliorates rotenone-induced Parkinson’s disease in mice via improving neuroinflammation and oxidative stress
Objective: The goal of the present study is to examine the neuroprotective property of hesperidin on rotenone-induced Parkinson's disease in mice. Background: The second most…
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