Istradefylline effect on Parkinson’s Disease Tremor, Motor symptoms and non-Motor symptoms.
Objective: Istradefylline is FDA approved for use in patients with PD treated with carbidopa-levodopa to reduce off time. GUH Movement Disorder Group has observed that…Gene-environment interactions for Parkinson’s disease
Objective: The aim of this study was to test for interactions between PD-related genetic and phenotypic traits in the 23andMe, Inc. research cohort. Background: Parkinson’s…Multiple N-of-1 trials to investigate hypoxia-based treatment in Parkinson’s disease: safety and short-term effects
Objective: In this study, we describe the safety and short-term effects of the first hypoxia-based treatment trial in Parkinson’s disease by deploying a personalized multiple…An IMU- based Objective Quantification Method for Bradykinesia Evaluation in Parkinson’s disease
Objective: Proposing an inertial measurement unit (IMU)-based objective quantification method for bradykinesia evaluation in Parkinson’s disease (PD) using MDS UPDRS III. Background: MDS-UPDRS III rating…Efficacy of subthalamic nucleus deep brain stimulation in Parkinson’s disease: A preliminary Thailand experience
Objective: To evaluate the efficacy and adverse events of subthalamic nucleus deep brain stimulation (STN-DBS) in Thai patients with Parkinson’s disease (PD). Background: Bilateral STN-DBS…Parkinsonian tremor secondary to Sinking flap syndrome – An atypical presentation
Objective: The association of sinking flap syndrome with Parkinsonian tremors is very rare Background: The association of sinking flap syndrome with Parkinsonian tremors is very…Validation of the Japanese version of the King’s Parkinson’s Disease Pain Scale and the King’s Parkinson’s Disease Pain Questionnaire
Objective: The purpose of this study is a validation of the Japanese version of the King's Parkinson's Disease Pain Scale (KPPS) and the King's Parkinson's…Building and evaluating a speech biomarker from 2-seconds sustained phonation to detect and monitor Parkinson’s disease
Objective: The aim of this work was to evaluate the feasibility of a speech-based algorithm geared towards frequent remote measuring of Parkinson’s disease severity with…Dopamine dysregulation syndrome in Parkinson’s disease controlled by safinamine
Objective: To describe a case of dopamine dysregulation syndrome managed by safinamide. Background: Dopamine dysregulation syndrome (DDS) is an uncommon non-motor symptom of Parkinson disease…Nocturnal behavior of people with Parkinson’s disease
Objective: Compare the nocturnal energy expenditure (kcal) and activity behavior of people with PD using a real-time wearable sensor, and determine whether these outcomes differed…
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