Functional circuit abnormalities in Levodopa-induced dyskinesia in Parkinson’s disease: A systematic review
Objective: Levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD) are involuntary movements caused by long-term treatment with dopaminergic replacement therapy (levodopa). During the cause of PD,…Impact of endpoint selection on sample size calculations for disease-modifying clinical trials in Parkinson’s disease patients with GBA1 mutations
Objective: To assess clinical trial sample size estimations under variable simulated scenarios for Parkinson’s disease (PD) patients with mutations in the β-glucocerebrosidade gene (GBA1). Background:…The effect of subthalamic deep brain stimulation on response inhibition and voluntary action control depend on connectivity of the volume of activated tissue with the prefrontal cortex
Objective: The effect of subthalamic deep brain stimulation on response inhibition and voluntary action control depend on connectivity of the volume of activated tissue with…No laughing white matter: reduced integrity of the lateral nucleus basalis of Meynert pathway in Parkinson’s disease-related cognitive impairment
Objective: Investigate differences in white matter integrity of the nucleus basalis of Meynert (NBM) tracts in Parkinson’s disease (PD) patients who develop mild cognitive impairment…What change to expect in duration of benefit per dose when switching from IR CD-LD to IPX203 (ER CD-LD)
Objective: To investigate if duration of benefit (“Good On” time) per dose during immediate-release (IR) carbidopa-levodopa (CD-LD) treatment predicts response to IPX203 conversion. Background: Levodopa’s…How do recently diagnosed individuals with Parkinson’s self-monitor their Parkinson’s symptoms between consultations?
Objective: To determine how recently diagnosed people with Parkinson's monitor their Parkinson's symptoms in between medical consultations. Background: Patients monitoring symptoms and reporting them accurately…How do people with Parkinson’s disease experience self-optimization of treatment using digitally supported symptom monitoring?
Objective: The aim of this study was to investigate how people with Parkinson´s disease experience an intervention of optimizing their own medical treatment through digitally…Influence of Cognitive Function on Obstacle-Crossing Performance in People with Parkinson’s Disease: A Cross-Sectional Study
Objective: This study investigated the influence of cognitive function on obstacle crossing performance in people with Parkinson's disease (PD). Background: Obstacle-crossing is a complex motor…White matter hyperintensities associated with impulse control disorders in Parkinson’s disease
Objective: Given the limited number of non-motor features studied in this context, our aim was to reveal the potential association between the severity of white…Making the invisible visible: A qualitative interview study on the impact of young onset Parkinson’s disease on (ex-)partners
Objective: This study aimed to explore the impact of having an (ex-)partner with young onset Parkinson’s disease (YOPD) on daily life. Background: People with YOPD…
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