Diabetes impact on nigrostriatal vulnerability in Parkinson’s Disease
Objective: aim of the study was to investigate whether diabetes mellitus influences nigrostriatal dopaminergic vulnerability in drug-naïve patients with early-stage Parkinson’s Disease (PD). Background: recently,…Combined GWAS of Dementia with Lewy Bodies, REM-Sleep Behavior Disorder, Parkinson’s Disease and Alzheimer’s Disease
Objective: To identify genetic variants that are either shared between or specific for Dementia with Lewy Bodies (DLB), REM Behavior Disorder (RBD), Parkinson’s disease (PD)…Sexual health and sleep quality in women living with Parkinson’s disease: are we neglecting that?
Objective: To investigate the relationship between sexual health and sleep quality in PD. Background: Sexual dysfunction (SD) is a common yet under-reported, non-motor symptom (NMS)…Olfactory neurons’ Substance P is highly expressed in Parkinson’s disease reflecting gastrointestinal dysfunction
Objective: To elucidate the role of Substance P in PD through molecular characterization of patients’ olfactory neurons. Background: Substance P is a neuropeptide largely expressed…Assessing akinesia domains during multitasking in Parkinson’s disease
Objective: To explore performance differences in single- versus dual-tasking conditions between healthy controls (HC) and Parkinson's disease (PD) patients. Background: Akinesia, comprising slowness (bradykinesia), reduction…Spinal cord stimulation for gait in Parkinsons disease in subthreshold settings
Objective: To assess optimal parameters for tonic spinal cord stimulation (SCS) for Parkinson’s Disease (PD) gait disorders in blinded settings. Background: SCS is a promising…Associations of IL-1β and IL-6 gene polymorphisms with Parkinson’s disease(PD)
Objective: We aim to explore the associations of IL-1β and IL-6 gene polymorphisms with the pathogenesis of PD and with clinical features of motor and…Efficacy and safety of safinamide in PD patients over 70 years vs. under 70 years old;
Objective: To search for any differences between efficacy and safety of safinamide in PD patients over 70 years vs. under 70 years old. Background: Safinamide…The specific application of a motor rehabilitation package in correcting the psycho-emotional sphere in patients with Parkinson’s disease.
Objective: The study aimed to investigate the effectiveness of a motor rehabilitation programme for 48 patients with Parkinson's disease using the phenomenon of paradoxical kinesia…Evidence of Central Autonomic Network dysfunction in orthostatic hypotension of Parkinson’s disease
Objective: To examine the contribution of the central autonomic network (CAN) to physiologic evidence of autonomic failure in Parkinson’s disease (PD). Background: Autonomic dysfunction, particularly…
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