Risk Tolerance of Therapeutic Interventions in People with Parkinson’s Disease
Objective: To determine the sociodemographic factors of people with Parkinson’s disease (PD) associated with risk tolerance when considering interventions. Background: Gender and racial disparities in…Hierarchical Machine Learning Classification of Parkinsonian Disorders using Saccades
Objective: To evaluate the discriminative power of a novel saccade waveform reconstruction approach compared to conventional saccadic metrics in differentiating Parkinson's disease (PD), progressive supranuclear…Gender specificity in AI-Based Screening Diagnostics of Parkinson’s Disease (Brainphone Project)
Objective: The aim of this part the clinical study was to obtain better understanding of the relation of efficiency AI-based screening diagnositics service for Parkinson's…Digital health technology (DHT) derived features as sensitive measures of disease progression in early Parkinson’s disease under stable dopaminergic treatment
Objective: To evaluate the ability of DHT derived features from remotely collected active tests to measure disease progression in individuals with early Parkinson’s disease (PD)…Prevalence of Phosphorylated Alpha-Synuclein in Skin Biopsies of Essential Tremor Patients
Objective: To examine the prevalence of phosphorylated alpha-synuclein in nerve fibers in patients with essential tremor (ET) and ET plus. Background: Although Essential Tremor (ET)…Rare Variant Burden is Increased in Sporadic Late-onset Chinese Parkinson’s Disease Patients
Objective: We aim to study the rare variant burden in a panel of 29 Parkinson’s disease (PD) candidate genes (Table 1) in a cohort of…Genome-wide Assessment of Homozygosity in Parkinson’s Disease Across Diverse Ancestral Population
Objective: Our objective is to undertake the most extensive screening of the impact of homozygosity in Parkinson's disease (PD) etiology across diverse populations. We aim…Sleep Characteristics in Idiopathic and Genetic Parkinson’s Disease
Objective: To investigate sleep features among individuals with genetic subgroups of PD, including LRRK2 G2019S-PD, GBA-PD, and iPD (idiopathic PD with no known genetic variant). Background:…The Black and African American Connections to Parkinson’s Disease Study
Objective: BLAAC PD is a multi-center study recruiting Black and African American individuals with Parkinson’s Disease (PD) and healthy controls. The ultimate goal is to…Optogenetic Deep Brain Stimulation Rescues Motor Behavior in a Rat Model of Mild Parkinson’s Disease
Objective: To demonstrate feasibility and proof-of-concept for a bilateral rat model of Parkinson’s disease (PD) undergoing deep brain stimulation (DBS) of the subthalamic nucleus (STN)…
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