Responders to a Highly Challenging Balance and Gait Intervention in People with Parkinson’s Disease
Objective: To characterize responsiveness to a highly challenging balance and gait intervention (HiBalance) in participants with Parkinson's disease (PD). Background: Exercise potentially improves gait, balance,…An Innovative Approach Combining Transcranial Direct Current Stimulation and Speech Therapy for the Treatment of Dysphagia in Parkinson’s Disease.
Objective: Our study used a combined approach based on non-invasive neuromodulation and speech therapy to improve dysphagia in PD patients. Background: Dysphagia is one of…Breaking Barriers to Offer Evidence-Based Services for Patients with Parkinson’s Disease in South Africa
Objective: To provide evidence-based services for patients with Parkinson’s disease considering the burden of disease in South Africa (SA) and access, socio economic and technology…Quality of life assessment in patients with Parkinson’s disease
Objective: The objective of the study was to assess the quality of life in patients with Parkinson's disease (PD) and to establish statistical correlations with…A Phase 1b Randomized, Placebo-Controlled, Delayed-Start Trial of UB-312 in Synucleinopathies.
Objective: Assess safety and immunogenicity of UB-312 in a phase 1b trial in Multiple System atrophy (MSA) or Parkinson’s disease (PD). Background: Abnormal deposition of…Orthostatic hypotension in age-related neurodegenerative diseases: a bibliometric study from 2007 to 2023
Objective: This study aims to systematically assess the current landscape and evolving trends of research on orthostatic hypotension in the context of age-related neurodegenerative diseases…Impact of 24-hour Subcutaneous Levodopa/Carbidopa Infusion (ND0612) on Motor State Transitions Throughout the Day
Objective: Evaluate the effect of investigational ND0612 infusion on the daily number of, duration of, and transitions between PD motor states, as assessed by home…Exploring the Neuroprotective Effects of Diurnal Light Exposure in Early-Stage Parkinson’s Disease: A Longitudinal, Multi-Sensory Intervention Study
Objective: This study aims to explore the neuroprotective effects of controlled diurnal light exposure on neurodegeneration rates in early-stage PD patients, positing that light therapy…Selecting an Imaging Biomarker for a Multi-Arm Multi-Stage Trial of Disease-Modifying Treatments for Parkinson’s: The EJS ACT-PD Experience
Objective: To report on the selection of an imaging biomarker for a sub-study in a multi-arm, multi-stage (MAMS) platform trial for disease-modifying therapies (DMTs) in…PD-DigiCare: Enhancing referral decision-making for advanced treatment in Parkinson’s Disease through objective measurements and patient reported outcomes – a multicenter randomized controlled trial.
Objective: The overall aim is to compare the efficacy of using wearable devices versus standard of care in improving the timeliness of referrals to evaluation…
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