Orthostatic hypotension exacerbates gray matter atrophy related to REM sleep behavior disorder in de novo Parkinson’s disease
Objective: As the previous studies indicated that other factors including REM sleep behavior disorder (RBD) and olfactory dysfunction were also associated with cognitive decline and…Genetics of Parkinson’s Disease in Polish patients with positive family history-preeliminary study.
Objective: The aim of our study was to find genetic variants associated with the familial forms of Parkinson’s disease (PD) in Polish population. Background: PD…Clinico-genetic analysis of patients with Parkinson’s disease and GBA mutations from a tertiary care teaching centre in India
Objective: To describe the clinico-genetic association of PD patients with heterozygous GBA mutations (PDwG). Background: Parkinson’s disease (PD) is currently understood to be the outcome…Freezing of gait in Parkinson’s disease with glucocerebrosidase mutations: prevalence, clinical correlates and effect on quality of life
Objective: Mutations in glucocerebrosidase (GBA) can change the phenotype of Parkinson’s disease (PD). This study aimed to explore the clinical characteristics of freezing of gait…Preliminary Report on the efficacy of Allogeneic Bone marrow-derived Mesenchymal Stem Cells as a disease-modifying therapy for idiopathic Parkinson’s disease: Phase IIa double-blind, randomized controlled trial.
Objective: To select the safest and most effective number of repeat doses of allogeneic mesenchymal stem cells (MSC) delivered intravenously to slow the progression of…Cortical mean diffusivity changes in Parkinson’s disease with probable RBD
Objective: To investigate cortical mean diffusivity (cMD) as a sensitive measure to identify subtle microstructural cortical changes in Parkinson’s disease (PD) patients with probable REM…Design of a time-to-event study in GBA Parkinson’s Disease patients: Efficacy and safety of BIA 28-6156, an allosteric activator of beta-glucocerobridase (GCase)
Objective: To assess the efficacy of BIA 28-6156 in delaying clinically meaningful motor progression in PD patients who have a PD-risk associated variant in the…Impaired mitochondrial respiration as a peripheral tissue biomarker for stratifying idiopathic Parkinson’s disease
Objective: To determine whether structural and/or functional deficiencies of the mitochondrial respiratory chain (MRC) occur in the skeletal muscle of patients with idiopathic Parkinson’s disease…Parkinson’s Progression Markers Initiative (PPMI): Defining PD biology to accelerate PD therapeutics
Objective: The overall goal of PPMI is to identify, test and validate biomarkers of PD to accelerate therapeutic development throughout the PD continuum. Background: PPMI…Traveling through the telescope: a neuromuscular and a movement disorders reunion
Objective: We aim to raise awareness to an uncommon but possible combination of Parkinson Disease (PD) and Myasthenia Gravis (MG). Background: The co-occurrence of PD…
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