Safety and pharmacokinetics of anti-inflammatory NE3107 treatment in carbidopa/levodopa-treated patients with Parkinson’s disease: A phase 2a, double-blind, placebo-controlled study
Objective: To assess the safety, tolerability, and pharmacokinetics (PK) of NE3107 in carbidopa/levodopa (C/L)-treated patients with Parkinson’s disease (PD) Background: Disease-modifying therapies that augment the…Serum levels of IL-1β and interleukin 6 in Parkinson’s disease
Objective: We aim to assess IL-1 β and IL-6 serum levels in patients with PD and in controls and to explore their associations with clinical…Linking volume of tissue activated to neural oscillations in deep brain stimulation
Objective: Exploring the effect of deep brain stimulation (DBS) settings on neural oscillations in Parkinson’s disease (PD) patients with subthalamic nucleus (STN) DBS and their…At-home adaptive deep brain stimulation improves motor fluctuations and quality of life in patients with Parkinson’s disease: a single-blind randomized study
Objective: We evaluated the effect of at-home adaptive deep brain stimulation (aDBS) based on personalized neural biomarkers on motor symptoms and quality of life (QoL)…self-compassion, trait worry and sleep in parkinson’s disease (PD) patients
Objective: to evaluate possible interactions between measures ofself-compassion, trait worry and sleep in Parkinson’s Disease (PD) patients. Background: PD patients often experience states of persistent…p.Gln257Profs*27 mutation in progranulin gene in a patient with corticobasal syndrome – the importance of family history
Objective: To report a case of a family with a mutation in progranulin gene manifesting as corticobasal syndrome, frontotemporal dementia and parkinson's disease. Background: Corticobasal syndrome (CBS) is mostly…Sport based approach in patients with Parkinson’s disease
Objective: We describe our 2-year experience implementing a sport based approach in patients with Parkinson’s Disease (PD). Background: PD is a progressive neurological disorder. The…Expanding the reach of a telehealth psychotherapy hub to advance coordinated depression care for rural veterans with Parkinson’s Disease
Objective: To describe the ongoing implementation and expansion of a telehealth psychotherapy hub to treat depression in rural Veterans with PD. Background: Depression is common…Association between dysphagia and body mass index and his impact on the severity of anxiety in patients with Parkinson Disease
Objective: To describe the relation between dysphagia and body mass index and the increase in anxiety and depression in patients with parkinson’s disease. Background: Parkinson’s…High Intensity Interval Training for people with Parkinson’s disease: individual response patterns of (non-)motor symptoms and blood-based biomarkers – a crossover single-case experimental design
Objective: To quantify individual response patterns of motor symptoms to alternating exercise modalities, along non-motor functioning and blood biomarkers of neuroplasticity and neurodegeneration. Background: Physical…
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