Motor phenotype and disease burden among Parkinson’s disease patients of Addis Ababa, Ethiopia.
Objective: This study aims to characterize the motor phenotype of Parkinson’s disease (PD), compare disease severity and to determine quality of life among the different…Subthalamic Nucleus Deep Brain Stimulation in GBA-associated Parkinson Disease: Cognitive and motor follow-up of two clinical cases
Objective: To report the long-term motor and cognitive outcome of two patients with GBA-associated Parkinson’s disease (PD) who underwent STN-DBS surgery. Background: Recent studies suggest…Identification of xylopropamine as a potential dopamine D2 receptor agonist through computational drug discovery pipeline
Objective: This study aims to identify novel dopamine D2 receptor agonists through the computational drug discovery pipeline. Background: Parkinson's disease (PD) is a neurodegenerative disorder…Cognitive overlap between Parkinson disease (PD) and Alzheimer’s disease (AD) is associated with plasma biomarkers and their impact on regional cortical thickness (CT): An ONDRI Study
Objective: To investigate cognitive performance across the Parkinson-Alzheimer’s spectrum and its association with plasma biomarkers and regional CT. Background: While PD and AD are neurodegenerative…The predictive potential of circular walking in prodromal Parkinson’s disease
Objective: This study aims to provide quantitative markers of prodromal motor symptoms of idiopathic Parkinson’s disease (PD) from circular walking assessment with a single body-fixed-sensor.…Factors influencing voice function after deep brain stimulation in Parkinson’s disease
Objective: To assess the effect of Deep Brain Stimulation (DBS) on self-perceived changes of voice function in Parkinson’s disease (PD). Background: To date, the effect…A cross regional investigation into the effects of fractures on the quality of life for elderly people with Parkinson’s disease in rural India
Objective: The negative impact of Parkinson’s Disease (PD) is rising as the global population ages and fractures with PD are additional health burdens. In rural…Understanding the Mechanisms of Brain Dysfunction when Performing the Mental Rotation Task (MRT) in Stage 1 and Stage 2 EOPD using brain imaging
Objective: Our aim is to understand MRT abnormalities in PD using fMRI and whether it can be used as a clinical marker for disease progression…Impact of non-pharmacological strategies on progression in Parkinson’s Disease and Cognitive Impairment.
Objective: to determine the Impact of non-pharmacological strategies on progression in Parkinson's Disease and Cognitive Impairment. Background: PD is the second most common neurodegenerative disorder,…High Intensity Interval Training for people with Parkinson’s disease: individual response patterns of (non-)motor symptoms and blood-based biomarkers – a crossover single-case experimental design
Objective: To quantify individual response patterns of motor symptoms to alternating exercise modalities, along non-motor functioning and blood biomarkers of neuroplasticity and neurodegeneration. Background: Physical…
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