Caffeine Intake Interacts with Gene Variants in Parkinson’s disease
Objective: We investigate interactions of caffeine intake with PD risk variants and determine PD risk estimates in caffeine-drinkers carrying these variants. Background: Caffeine intake reduces…Impact of istradefylline on the onset of dyskinesia in Parkinson’s Disease patients with wearing off: a randomized controlled study (ODYSSEI)
Objective: To determine the effect of long-term treatment with istradefylline (IST) on the time to onset of dyskinesia in Parkinson’s disease (PD) patients with wearing-off…Imaging the noradrenergic system in Parkinson’s disease: A [11C]Yohimbine PET and neuromelanin MRI study
Objective: To assess two aspects of the noradrenergic system using multimodal in vivo imaging in a sample of Parkinson’s disease (PD) patients and healthy controls…PD.ai – Detection of Parkinson’s Disease with gait-based biomarkers using AI techniques
Objective: This study evaluated the utility of Artificial Intelligence (AI) in detection of patients with Parkinson’s disease from stride dynamics. Background: Parkinson’s Disease (PD) is…Predictive model for Identification of device-aided therapy (DAT) Candidates in Parkinson´s Disease (DELIST-PD Study)
Objective: To develop a classification algorithm based on machine learning to identify candidates for device-aided therapy among patients with Parkinson's disease (PD). Background: DATs (deep…Oculomotor parameters measured during free viewing of video differentiate Parkinson’s disease from progressive supranuclear palsy
Objective: Characterize oculomotor phenotypes comprised of saccade, pupil, and blink behaviour for progressive supranuclear palsy (PSP) and Parkinson’s disease (PD) with differing degrees of cognitive…Can radiofrequency lesion be better than DBS?
Objective: Pallidotomy represents a viable alternative for Parkinson disease(PD) symptoms treatment and has several important advantages, including a decreased need for access to specialists and clinical follow-up, improved affordability, and a lower infection risk, producing high long-term success rates and low morbidity rates. Background: Pallidotomy is recognized as effective for treating the symptoms of Parkinson's disease. Sometimes, radiofrequency may…Comparing the outcome under General Anaesthesia (GA) and Monitored Anesthesia Care (MAC) of Subthalamic Nucleus (STN) – Deep Brain Stimulation (DBS) Surgery for Parkinson’s Disease (PD) in Hong Kong – A single center experience
Objective: To evaluate any difference in the clinical outcome under GA and MAC of STN DBS surgery Background: Traditionally, DBS surgery is performed under MAC…The spectrum of GBA mutations in the Korean population with Parkinson’s disease
Objective: We investigated the mutation spectrum of glucocerebrosidase (GBA) gene in Korean patients with Parkinson’s disease (GBA-PD). Background: Mutations in the GBA gene represent important…Morphometric assessment of age-associated neuronal changes in the human locus coeruleus
Objective: To delineate the age-related changes in the neuronal size and neuromelanin (NM) intensity in autopsied tissues of human locus coeruleus (LC). Background: Many studies…
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