Selegiline drives autophagic secretion of α-synuclein
Objective: Our aim is to elucidate how selegiline drives extracellular secretion of α-synuclein (αS) and whether selegiline-induced αS secretion affects cell-to-cell transmission of αS. Background:…User Experience (UX): Successful Remote Engagement Strategy for Individuals at Risk for Parkinson’s Disease in PPMI
Objective: Describe participant engagement practices for progressive User Experience (UX) in a remote risk screening study. Background: Digital instruments continue to gain footing in clinical…A Comparison of Cervical Dystonia in Parkinson’s Disease and Idiopathic Isolated Cervical Dystonia
Objective: To perform a prospective analysis of the prevalence and clinical characteristics of cervical dystonia in Parkinson’s disease (CD-PD) and compare these features to those…Validation of the Patient Reported Outcomes in Parkinson’s Disease scale in outpatients
Objective: To validate PRO-PD in a random sample of outpatients with PD. Background: Successful treatment of Parkinson's disease (PD) requires symptom monitoring. Patient-Reported Outcomes in…Apomorphine effects on Parkinson’s disease fluctuation related pain: a pilot study
Objective: To evaluate the effect and safety of subcutaneous apomorphine as a treatment for fluctuation-related pain in Parkinson's disease (PD). Background: Pain is one of…Aspects of early detection of parkinson`s disease in ambulatory settings
Objective: Evaluation of the role and value of a special computer program for early detection of PD in ambulatory settings Background: The first symptoms of…Dysphagia and dopaminergic neurodegeneration in Parkinson’s Disease
Objective: To evaluate the association between dysphagia and neurodegeneration of the putaminal dopaminergic system in people with early-stage treated with symptomatic therapy and advanced-stage Parkinson’s…Correlation of Functional Motor Assessments Used at Parkinson’s disease by Physiotherapists in Clinical Practice
Objective: The aim of this study was to verify whether there is a correlation between UPDRS motor score and non-specific assessments for PD commonly used…Caffeine Intake Interacts with Gene Variants in Parkinson’s disease
Objective: We investigate interactions of caffeine intake with PD risk variants and determine PD risk estimates in caffeine-drinkers carrying these variants. Background: Caffeine intake reduces…Impact of istradefylline on the onset of dyskinesia in Parkinson’s Disease patients with wearing off: a randomized controlled study (ODYSSEI)
Objective: To determine the effect of long-term treatment with istradefylline (IST) on the time to onset of dyskinesia in Parkinson’s disease (PD) patients with wearing-off…
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