Cerebello-Thalamo-Cortical Tract Microstructural Changes in Parkinson’s Disease Patients with Tremor
Objective: To evaluate microstructural characteristics in the cerebello-thalamo-cortical circuit (CTC) of Parkinson's Disease (PD) patients with different tremor phenotypes. Background: Tremor is one of the…Description Genotype/phenotype of patients with Parkinson’s disease. Report of an Argentinean cohort included in the LARGE PD Consortium.
Objective: To characterize the genetic and phenotypic profile of Argentinean Parkinson's patients and contribute to the understanding of the genetic heterogeneity of this disease. Background:…Investigating the Global Genetic Spectrum of Monogenic Parkinson’s Disease and Parkinsonism
Objective: To investigate known pathogenic and risk variants linked to Parkinson’s disease (PD) at a global, multi-ancestry scale. Background: Genetic forms of PD have been…Non-motor Symptoms, Sleep Disturbances, And Genetic Insights In Young Onset Parkinson’s Disease: A Prospective Descriptive Study
Objective: 1. To study the prevalence of various non-motor symptoms in Young onset Parkinson's Disease patients2. To study the genetic markers in YOPD patients. Background:…Clinical Differences Among Parkinson’s Disease Patients Carrying GBA1 Variants in Colombia: Insights From LARGE-PD Consortium
Objective: To compare the clinical manifestations of GBA1 variants p.K198E, p.E326K, and p.N370S in Parkinson’s disease(PD) patients in Colombia. Background: GBA1 variants have been identified…Assessing Individual Risk Through Determination of Local Ancestry: Insights from the Global Parkinson’s Genetics Program
Objective: We're developing a scalable pipeline to infer local ancestry (LA) for individuals in the Global Parkinson's Genetics Program (GP2). This approach aims to enhance…Screening for GBA1 p.K198E PD-Risk Variant in Latin America
Objective: We aimed to assess the distribution of the GBA1 p.K198E variant, linked to Gaucher’s disease (GD) and increased Parkinson’s disease (PD) risk, across Latin…DBS Programming in Early Simultaneous STN-GPi Implantation for Young-Onset Parkinson’s: A Mini Case Series
Objective: We aim to present our institution's experience with simultaneous dual STN-GPi implantation in Parkinson’s disease (PD) by analyzing a case series of 3 patients.…Impact of Insurance and Risk Factors on DBS Outcomes
Objective: Assess the effect of insurance type on deep brain stimulation (DBS) outcomes, and identify risk factors for progression to assisted ambulation and dependency (home…Pallidotomy Reborn? Revisiting GPi Lesions in the Era of Neuro modulation for Parkinson’s Disease
Objective: To compare motor outcomes, surgical considerations, and follow-up data between unilateral GPi-DBS and GPi-RF pallidotomy in Parkinson’s disease (PD), evaluating their long-term efficacy and…
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