A pooled analysis of four pivotal, randomized controlled trials of istradefylline, an adenosine A2A receptor antagonist: Efficacy as adjunct to levodopa in Parkinson’s disease (PD)
Objective: To determine the efficacy of istradefylline combined with levodopa in PD patients experiencing motor fluctuations in a pooled analysis of 4 pivotal, randomized, placebo-controlled…Outcome Profiles in Advanced Parkinson’s Disease Patients Treated With Long-Term Levodopa-Carbidopa Intestinal Gel in a Routine Clinical Practice: Analysis From the COSMOS Study
Objective: To describe the characteristics and outcomes of advanced Parkinson’s disease (PD) patients grouped by treatment duration of levodopa-carbidopa intestinal gel (LCIG, carbidopa-levodopa enteral suspension[CLES],…Apomorphine subcutaneous infusion reduces dopaminergic dosage whilst maintaining motor benefits in Parkinson’s disease: A prospective analysis of Thai Apomorphine Registry
Objective: To evaluate a reduction of LED in PD patients who achieve satisfactory motor control with long-term continuous subcutaneous apomorphine infusion (CSAI) Background: Apomorphine is…Morphology and Signal Changes of the Lentiform Nucleus Based on Susceptibility Weighted Imaging in Parkinsonism predominant Multiple System Atrophy
Objective: This present case-control study was aimed to investigate both morphological and signal intensity changes in susceptibility weighted imaging(SWI) of the Lentiform Nucleus (LN) for…Potential Diagnosis Biomarks in Serum Biochemical items of Vascular Parkinsonism Patients
Objective: Evaluating the serum biochemical items for diagnosis of vascular parkinsonism. Background: Currently, the most effective diagnostic methods for VP are mainly based on clinical symptoms.…Movement Disorders Analysis Using a Deep Learning Approach
Objective: Using a deep learning inspired approach, we developed a tool to compute an objective score of bradykinesia. Background: Bradykinesia is defined as a motor…Respiratory training in Parkinson’s disease: a systematic review
Objective: This systematic review provides an overview investigating the effects of different respiratory training interventions in Parkinson’s disease (PD). Background: Signs of respiratory dysfunction are…Loneliness/Social Isolation as a Risk Factor for Worsened Parkinson Disease Severity
Objective: The goal of this project was to evaluate the association between self-reported loneliness, quality of life, and patient-reported symptoms of Parkinson’s disease (PD) severity.…Neuroimaging Software Assisted Deep Brain Stimulation (DBS) Programming in Patients with Parkinson’s Disease (PD)
Objective: To compare DBS programming results by novel neuroimaging software assisted programming approach versus standard of care approach in PD patients. Background: Traditional DBS programming…Twiddler’s Syndrome in Deep Brain Stimulation
Objective: We describe a case of Twiddler’s syndrome in a patient who underwent DBS surgery. Background: Twiddler’s syndrome was first described in 1968 in cardiac…
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