Gender differenes in cognitive functioning in de novo Parkinson’s disease patients
Objective: To clarify the differences in cognitive functioning across different cognitive domains, between male and female de novo PD patients. Background: Parkinson’s disease (PD) is…Optic atrophy and parkinsonism in a family associated with OPA1 mutation
Objective: To report a Taiwanese family with a heterozygous missense mutation of OPA1 gene (NM_130836, p.Ser582Arg) presenting with optic atrophy and parkinsonism and establish an…Whole exome trio analysis in isolated population of southeast Moravia (Czech Republic) with familial parkinsonism suggests its heterogeneous genetic background
Objective: The aim of the study was to identify shared genetic variants potentially associated with familial neurodegenerative parkinsonism using whole-exome analysis. Background: Increased prevalence of…ADAM10 polymorphisms are not associated with susceptibility to Parkinson’s disease and Parkinson’s disease with cognitive impairment in a Chinese cohort
Objective: This study is to explore the relationship between the rs442495 and rs593742 loci of ADAM10 gene and Parkinson's disease( PD) or PD cognitive impairment.…The feasibility of detailed phenotyping of muscle mitochondrial respiratory chain function and content in Parkinson’s disease
Objective: We aimed to determine: 1) the feasibility of obtaining and characterising skeletal muscle; and 2) if muscle mitochondrial respiratory chain (MRC) function and content…Magnetic Property Characterization of Deep Gray Matters in Patients with Alzheimer’s diseases, Dementia with Lewy Bodies and Parkinson’s Disease Dementia using Quantitative Susceptibility Mapping
Objective: The purpose of this study was to characterize magnetic properties of deep gray matters in Alzheimer's diseases (AD), dementia with Lewy bodies (DLB) and…Dual hit model of Parkinson’s disease propagation using MRI biomarkers and partial least squares path modeling
Objective: This study aimed using multimodal MRI to test two models of Parkinson’s disease propagation and investigated how the models were influenced by the presence…Predicting Longitudinal Atrophy in Parkinson’s Disease using SIR model
Objective: To predict longitudinal brain changes in Parkinson's disease (PD) using an agent-based model. Background: Considerable evidence suggests that α-synuclein(α-syn) behaves in a prion-like fashion,…Differences in subthalamic oscillatory neuronal activity associated with severity in Parkinson’s disease
Objective: To investigate whether altered neuronal activity in the subthalamic nucleus (STN) is associated with severity in patients with Parkinson’s disease (PD). Background: PD is…Sex-related disease differences in Parkinson’s disease
Objective: To highlight differences in clinical disease parameters between sexes in a cohort of Parkinson’s disease (PD) patients. Background: PD is a progressive neurodegenerative disorder…
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