Meynert Nucleus-related Cortical Thinning in Parkinson’s Disease with Mild Cognitive Impairment
Objective: To investigate the associations between NBM/Ch4 volume and cortical thickness in PD. Background: Cognitive impairment in Parkinson’s disease (PD) involves the cholinergic system, especially the…Moderately frequent and private variants in PRKN are associated with late-onset Parkinson’s disease
Objective: We hypothesized that heterozygosity for rare coding variants in PRKN, PINK1 or PARK7 might also represent a risk factor for sporadic late-onset PD.[4] Background:…Early predictors of Parkinson’s disease and prognosis in relatives
Objective: To study early clinical and biochemical markers of Parkinson's disease (PD) in relatives of Uzbek nationality. Background: Parkinson's disease is a neurodegenerative hereditary disease…Utility of multigene panel testing for diagnosing parkinsonism and dystonia in a large cohort of >500 patients
Objective: Evaluate the utility of multigene Next-Generation Sequencing (NGS) for molecular diagnosis of parkinsonism and dystonia. Background: Parkinson's disease (PD) and dystonia are common neurodegenerative…Detection of alpha-synuclein aggregation from submandibular and esophageal tissue of patients with synucleinopathies
Objective: Utilize cyclic amplification methods to facilitate detection of aggregation prone forms of a-syn from submandibular or esophageal tissue of patients with syncleinopathies. Background: In…Deep learning-based automatic nigrosome 1 segmentation on 3T susceptibility-weighted MRI
Objective: The aim of this study was to develop a deep learning-based system for automatic nigrosome 1 segmentation on susceptibility-weighted imaging (SWI) from 3T magnetic…The clinical significance of the swallow tail sign in distinguishing Parkinson’s disease patients from healthy individuals
Objective: To investigate whether the absence of the swallow tail sign can be applied for distinguishing PD patients from healthy individuals. Background: With conventional MRI,…Dysfunction in superior frontal gyrus associated with diphasic dyskinesia in Parkinson’s disease
Objective: We aimed to explore alterations in regional brain function associated with diphasic dyskinesia in Parkinson’s disease (PD). Background: Levodopa-induced dyskinesia (LID), which is a common…Analysis of pupillometer results according to motor symptoms severity in Parkinson’s disease patients
Objective: To investigate the value of pupillometric parameters according to the progress of Parkinson’s disease (PD). Background: Pupil light reflex is known to be associated…Alexithymia is associated with worse quality of life and caregiver burden in people with Parkinson’s disease
Objective: Aim of the present study was to determine the relationship of alexithymia on HR-QoL of the PwP and caregiver burden of the corresponding primary…
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