Implementation of the ParkinsonNet care concept shows better expertise and work satisfaction of health professionals, but improvement of multidisciplinary collaboration takes longer than one year
Objective: To evaluate the changes in perceived quality of care for people with Parkinson’s disease (PD) among health professionals (HPs) in Luxembourg at one year…Disparities in access to care and research participation among individuals with advanced Parkinson’s Disease: Comparison of participants in a home visit model vs. national registry
Objective: We sought to identify whether those with advanced Parkinson’s disease (PD) who become homebound are sociodemographically different than those who continue to attend outpatient…Primary familial brain calcifications in Sweden
Objective: Our main aim was to define the clinical presentation and genotypes of a cohort with primary familial brain calcifications (PFBC) at a tertiary center…Say “AH~”: Vocal Analysis in Parkinson’s Disease and Essential Tremor
Objective: We aimed to investigate useful vocal parameters in differentiating PD and ET, using a machine-learning algorithm. Background: Correlation between Parkinson's disease (PD) and essential tremor (ET)…The role of dementia in Parkinson’s disease
Objective: To identify cognitive and visual-spatial disorders in patients with Parkinson's disease. Background: In the clinical picture of Parkinson's disease, non-motor symptoms acquire great importance,…Cerebrospinal fluid protein markers of cognition in early Parkinson’s disease
Objective: The aim of this multicenter study was to investigate potential alterations of CSF protein levels associated with overall and domain-specific cognitive performance in early…Cerebral microvascular injury provoked by alpha-synuclein preformed fibrils exacerbates cognitive dysfunction in Parkinson’s disease
Objective: The aim of this study was to investigate the role of microvascular pathology between abnormal αSyn aggregation and PD cognitive dysfunction. Background: Higher plasma…Enriched burden of rare coding variants in hereditary parkinsonism genes in Parkinson’s disease
Objective: Under a hypothesis that a burden of damaging rare coding variants is increased in causative genes for hereditary parkinsonism, we analyzed burdens of rare…LRRK2 p.G2019S and p.N2081D variants as modifiers of glucocerebrosidase activity
Objective: To examine whether the activity of the lysosomal enzyme glucocerebrosidase (GCase) is associated with LRRK2 variants. Background: Mutations in GBA (which encodes GCase) and…Loss of CHCHD2 and CHCHD10 disrupts mitochondrial cristae phenocopying patient mutations
Objective: Characterization of novel of a novel CHCHD2 (C2) and CHCHD10 (C10) knockout mouse model. Background: Dominant mutations in the mitochondrial paralogs CHCHD2 (C2) and…
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