H1/H2 MAPT Haplotype and Parkinson’s Disease in an Ashkenazi Jewish Cohort
Objective: To study the Microtubule-Associated Protein Tau (MAPT) H1/H2 haplotype contribution to clinical manifestation of Parkinson’s disease (PD) in an Ashkenazi Jewish (AJ) cohort, focusing…Clinical and Genetic Characteristics of the University of Pennsylvania Parkinson’s Disease Population: Results from the Molecular Integration in Neurological Diagnosis (MIND) Initiative
Objective: To describe the clinical characteristics and the frequency of GBA and LRRK2 variants in the Parkinson’s disease (PD) patient population at The University of…Impaired Structural Connectivity in Parkinson’s Disease and its Neuropsychological Correlates
Objective: The aim of this study was to detect disrupted structural connectivity in Parkinson's disease (PD) patients classified according to their cognitive status, with and…Functional connectivity of the basal ganglia in tremor dominant and non-tremor dominant Parkinson’s disease
Objective: To explore differences in functional connectivity of the basal ganglia in tremor dominant and non-tremor dominant Parkinson’s disease (PD) using seed-to-voxel based resting state…Microstructural changes in GBA mutation carriers with depression
Objective: To investigate structural changes associated with depression in glucocerebrosidase (GBA) mutation carriers. Background: Depression is a common non-motor symptom in Parkinson’s disease (PD); however,…Wearable sensor monitoring in denovo Parkinson’s disease using the Parkinson’s KinetiGraph: pilot data and correlations from the MoNS-PD cohort
Objective: To describe Parkinson’s kinetograph utilised clinical parameters and correlations in a denovo Parkison’s disease (PD) cohort from Moscow Russia. Background: The Parkinson’s KinetiGraph™ (PKG)…Effect of regular practice of yoga versus aerobic exercise on motor and non motor signs and motor cortex plasticity in Parkinson’s disease
Objective: To test whether the regular practice of yoga (1) improves motor and non-motor symptoms and signs in Parkinson’s disease (PD) more than aerobic training…Apathy as a non-motor symptom(NMS) in patients with Parkinson’s disease(PwPD) and patients with Huntington’s disease(PwHD) in Tomsk, Russia
Objective: The aim is to evaluate and compare the apathy profile in PwHD and PwPD, using the same clinical criteria to assess the severity of…Unmet psychological needs of People with Parkinson’s disease
Objective: To investigate whether Parkinson’s disease (PD) specialists are identifying patients with Parkinson’s psychological needs and referring them to appropriate services. Background: A number of…Spreading ɑ-synuclein pathology initiated from the sublaterodorsal tegmental nucleus models RBD followed by Parkinsonian phenotypes in mice
Objective: To recapitulate ɑ-synucleinopathy based RBD-like behaviors in mice which could further proceed to develop Parkinsonian behavioral and histopathological phenotypes. Background: Idiopathic REM sleep behavior…
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