Impulse control disorders in idiopathic REM sleep behaviour disorder and drug-naive Parkinson’s disease
Objective: To compare the frequency of impulse control disorders and compulsive behaviours (ICBs) in patients with iRBD and drug-naive PD, and to identify risk factors…Childhood-Onset Hemidystonia: A Transportophaty related to SLC6A3 missense mutation
Objective: To present the case of a childhood-onset hemidystonia carrying a homozygous SLC6A3 missense mutation. Background: Dystonia is a movement disorder characterized by sustained or…Akinetic-rigid motor presentation among adult-onset HD participants in Enroll-HD
Objective: To characterize a variant of adult Huntington’s disease (HD) with akinetic-rigid syndrome (ARS) as initial motor manifestation Background: HD Cases have been reported with…Long-Term Safety and Efficacy of Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease
Objective: Evaluate long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD).…Impact on Dyskinesia in Advanced Parkinson’s Disease Patients Treated with LCIG: Analysis from the COSMOS Study
Objective: Analyze the impact of levodopa-carbidopa intestinal gel (LCIG) treatment on dyskinesia duration and severity in advanced Parkinson’s disease (APD) patients participating in the COSMOS…Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
Objective: We employed Quantitative susceptibility mapping (QSM) to assess iron deposition in a larger sample size and explore whether combining QSM and NfL can improve…A case of dystonia-parkinsonism associated with a heterozygous PRKRA (DYT16) gene mutation
Objective: We describe the clinical presentation, diagnosis, and treatment of a case of dystonia-parkinsonism associated with a heterozygous mutation in the initiator methionine of the…Perivascular spaces in the basal ganglia and long-term motor prognosis in newly diagnosed Parkinson’s disease
Objective: To investigate the association between enlarged perivascular spaces (PVSs) in the basal ganglia (BG-PVSs) and long-term motor outcomes in Parkinson’s disease (PD). Background: PVSs…Mood is a Key Factor in Progression of Non-Motor Symptoms Burden in Parkinson´s disease.
Objective: The aim of the present study was to identify predictors of non-motor symptoms burden non-progression (NMSB-NP) in PD patients from a Spanish cohort [1,2].…Maximising UPDRS information while minimising assessment time
Objective: The gold standard for measuring disease severity in PD (Parkinson’s Disease) is the MDS-UPDRS (Movement Disorder Society - Unified PD Rating Scale) [1]. However,…
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