Reduced thalamo-cortical functional connectivity in asymptomatic LRRK2 mutation carriers
Objective: To characterize MRI functional patterns during resting state in asymptomatic LRRK2 mutation carriers. Background: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are…Vitamin D receptor polymorphisms and Parkinson’s disease in a Korean population: Revisited
Objective: We evaluated an association between PD and VDR polymorphisms including BsmI, FokI, ApaI, and TaqI and we also investigated the relationship between VDR polymorphisms…The French experience of liver transplantation for severe neurological forms of Wilson disease
Objective: To evaluate the efficacy of liver transplantation (LT) in patients with severe neurological forms of Wilson disease (WD) who got clinically worse despite a…Toward a new biomarker on Parkinson’s disease: Study of alpha synuclein on upper enteric system by endoscopy
Objective: The aim of our study was to investigate the alpha synuclein deposition at the enteric nerve system on patient with Parkinson's disease and provide…Different patterns of spontaneous brain activity between tremor-dominant and postural instability/gait difficulty subtypes of Parkinson’s disease: A resting-state fMRI study
Objective: This study aimed at investigating the subtype-specific patterns of spontaneous brain activity in PD. Background: Postural instability/gait difficulty (PIGD) and tremor-dominant (TD) subtypes of…A novel C. elegans model for identification of small molecules that target alpha-synuclein-mediated toxicity
Objective: To develop a novel transgenic C. elegans model to study dopaminergic neurodegeneration mediated by alpha-synuclein. Background: Targeting alpha-synuclein could be a disease-modifying strategy for…Changes in serum amino acid levels with progression of Parkinson’s disease
Objective: The purpose of this study was to analyze changes in serum amino acid profile with progression of Parkinson's disease (PD). Background: PD is a…Exploring aging-VMAT2 gene-rotenone interactions in a cell model for Parkinson’s disease
Objective: To develop a Parkinson's disease (PD) model based on aging, vesicular monoamine transporter 2 (VMAT2) gene susceptibility and chronic rotenone exposure in SK-N-SH cell,…Manganese-induced parkinsonism and motor neuron damage- Can there be a relationship?
Objective: The aim of the study was evaluation of clinical, radiological and ENMG characteristic of ephedronic encephalopathy(EE). Background: The ephedrone abuse is widely spread among…Functional connectivity underpinnings of fatigue in “drug-naïve” patients with Parkinson’s disease
Objective: Using resting-state functional MRI, we investigated the functional correlates of fatigue in a cohort of “drug-naïve”patients with PD. Background: Fatigue is a common problem…
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