IL-6 and motor symptoms in Parkinson’s disease
Objective: To assess the concentration of interleukin-6 (IL-6) in serum of patients with PD and its relation to motor symptoms. Background: Participation of inflammatory mechanisms…LC3 deacetylation by SIRT1 is involved in neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson’s disease
Objective: Our previous study has demonstrated that resveratrol (RV) enhanced clearance of misfolded α-synuclein proteins in cellular models of PD, with the activation of SIRT1…Involvement of peripheral immune system in the pathogenesis of Parkinson’s disease
Objective: To investigate the role of peripheral immune system in the pathogenesis of Parkinson's disease carrying LRRK2 risk variants. Background: Leucine-rich repeat kinase 2 (LRRK2)…Oral apomorphine film (APL-130277) produces no buccal mucosal irritation: Results of a toxicological study
Objective: Determine the tolerance of and potential for cheek pouch buccal mucosa irritation following the administration of apomorphine film (APL-130277). Background: APL-130277 is a sublingual…Exosomes-injection to reproduce a mouse model of Parkinson’s disease: A preliminary report
Objective: To explore the pathogenicity of exosomes derived from Parkinson's disease (PD) patients' serum and healthy control's serum in vivo and verify the prion-like propagation…Tremor frequency by iPhone® applications: Correlation with EMG analysis
Objective: To compare tremor frequency obtained by EMG and accelerometry analysis with three iPhone® applications. Background: Frequency as a property of tremor is a vital…PET examination of the monoamine transporter with 11C-beta-CIT
Objective: To investigate the utility of 11C-β-CIT PET scan on Parkinson's disease diagnosis. Background: The monoamine reuptake sites transport dopamine, noradrenaline and serotonin from the…Interrelation between gait impairment with cognitive disturbances in patients with Parkinson’s disease
Objective: To study interrelation of neuropsychological disturbances with severe gait impairment and postural stability in Parkinson's disease. Background: Clinical features of gait impairment and postural…Brain iron levels in Parkinson’s disease by postmortem and MRI measurements: A systematic review and meta-analysis
Objective: In this study we performed a systematic review and meta-analysis aiming to understand PD-associated iron variations in all brain regions that have been examined,…Diagnostic reliability of clinical symptoms in patients with incomplete manifestation of the triad of parkinsonism compared to 18F-DOPA PET-CT MRI imaging
Objective: To describe the diagnostic reliability of the triad of clinical symptoms compared to the uptake of 18 F-DOPA PET-CT fusion MRI scan. To compare…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.