Increased anti-MAG autoantibodies titers in Parkinson’s disease
Objective: To search for biomarkers of neurodegenerative process in Parkinson's disease (PD).There is emerging evidence that humoral response may be involved in the pathogenesis and…Hyperin inhibits lipopolysaccharide-induced microglia activation through p38 and NFκB signaling
Objective: In this study, we aimed to investigate hyperin's potentiality in inhibition of neuroinflammation. Background: Hyperin is an active compound isolated from Rhododendron brachycarpum G.…Constipation in early de novo Parkinson’s disease: Prevalence and correlates with clinical features, imaging and non-imaging biomarkers
Objective: To explore the association between constipation and clinical features, imaging and non-imaging biomarkers in early de novo (untreated) Parkinson's disease (PD) patients. Background: Constipation…Diffusion tensor imaging biomarkers of nigrostriatal neurodegeneration in early Parkinson’s disease
Objective: Identify magnetic resonance imaging (MRI) biomarkers of nigrostriatal neurodegeneration in early-stage drug-naïve Parkinson's disease (PD). Background: Diffusion tensor imaging (DTI) is an MRI technique…Is levodopa-induced dyskinesia in Parkinson’s disease associated with increased blood brain barrier permeability and volumetric changes?
Objective: The aim of this study was to explore the angiogenetic hypothesis for Levodopa-induced-dyskinesia (LID) using advanced MRI methods in patients with Parkinson's disease (PD).…1 to 40 years later: Delayed effects of brain radiation presenting as parkinsonism
Objective: To report 3 adult cases of delayed radiation induced parkinsonism, with latency ranging from 1 to 40 years. . Background: Unequivocal radiation induced parkinsonism…Fragile X-associated tremor/ataxia syndrome in two female patients
Objective: To report two cases of female patients with FXTAS. Background: Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder with core features of action…Transcranial sonography of the substantia nigra and its correlation with iron metabolism and c-reactive protein in Parkinson’s disease
Objective: To measure the echogenicity of the substantia nigra (SN) by transcranial sonography (TCS) in PD patients and discuss its correlation with iron metabolism and…Real world conversion of levodopa to a novel extended release levodopa preparation: Determining predictors and dose ratios
Objective: To determine predictors of response and conversion ratios for a novel extended release levodopa preparation. Background: A new extended release levodopa preparation, Rytary®, has…Disrupted hubs in functional brain networks in subtype-specific Parkinson’s disease
Objective: To detect the changing pattern in functional network hubs in subtype-specific Parkinson's disease (PD) using resting-state functional magnetic resosonce imaging (Rs-fMRI). Background: PD is…