Symptom progression in a large cohort of Parkinson’s disease cases in a clinical practice setting
Objective: To assess the temporal profile of motor and non-motor symptoms in Parkinson's disease. Background: Parkinson's disease is characterized by varying combinations of motor and…An update on genotype-phenotype correlation in X-linked dystonia-parkinsonism (XDP/DYT3)
Objective: To further characterize the severity, movement abnormalities, and disease course in an expanded cohort of subjects and their families with XDP and determine if…Has iCare PD started in Singapore?
Objective: To evaluate if interdisciplinary care (iCare) is present in the management of Parkinson's disease (PD) among PD Allied Health Professionals (AHP) at a centre…The neurosteroid dehydroepiandrosterone sulfate (DHEAS) reverses the dopaminergic deficiencies in mild hepatic encephalopathy: A possible therapeutic issue for the management of parkinsonism in cirrhotic patients
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…A national case study of virtual care visits for Parkinson’s disease (RACE-PD): Interim assessment of participant and investigator experiences
Objective: RACE-PD is a case series that aims to assess the feasibility and utility of a national program providing individuals with Parkinson's disease (PD) a…Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3beta activity
Objective: To identify disease-modifying therapy for LRRK2-G2019S parkinsonism. Background: Leucine-rich repeat kinase 2 (LRRK2) is the most common genetic cause of Parkinson's disease (PD) without…Effect of pharmacist-led interventions on motor symptoms and quality of life in Parkinson’s patients: A pilot study
Objective: Improvement of on-off symptoms in ambulatory patients with Parkinson's disease (PD) by introduction of a multi-faceted medication optimization program. This consisted of a patient…Effects of plantar automated mechanical stimulation (AMPS) on motor symptoms of patients with advanced Parkinson’s disease: Preliminary data of a double blind randomized clinical trial
Objective: To evaluate the effect of one session treatment with autometed mechanical peripheral stimulation (AMPS) on gait and motor functions of patients with advanced Parkinson's…Objective measures of Parkinsonian motor symptoms using a continuously worn smartwatch
Objective: To determine whether smartwatch sensor data correlates with clinician-measured Parkinson's disease symptoms. Background: Data collected with smartwatches could be used for long-term, continuous assessment…A randomized clinical trial of atomoxetine treatment for mild cognitive impairment (MCI) in Parkinson’s disease (PD)
Objective: To evaluate (1) safety and tolerability of ATM and (2) effects of ATM on attention and executive functioning in PD- MCI after 10 weeks…
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