Unusual phenotype of pathologically confirmed progressive supranuclear palsy with autonomic dysfunction and cerebellar ataxia
Objective: To report two cases of patients with unusual manifestation of pathologically confirmed PSP. Background: Based on the results of recent multicenter clinical-pathological studies, it…Multimodal voxel-based analysis of the infratentorial brain region in Richardson’s syndrome, progressive supranuclear palsy-parkinsonism, Parkinson variant of multiple system atrophy and Parkinson’s disease
Objective: Voxel-based analysis was applied to MRI parameters of iron content (transverse relaxation rate, R2*), microstructural integrity including mean diffusivity (MD) and fractional anisotropy (FA)…Motor features and response to levodopa in Parkinson’s disease with normal olfactory function
Objective: The aim of this study was to evaluate motor features in the OFF and ON states and the acute levodopa response in Parkinson's disease…Hypothalamic volume loss is associated with reduced melatonin output in Parkinson’s disease
Objective: Our aim was to compare hypothalamic volumes in PD patients with matched controls, and determine whether volume loss correlated with reduced melatonin output in…Characterization of sleep disturbances in a prospective population-based cohort to investigate Parkinson’s disease
Objective: To study sleep disturbances in Parkinson's disease (PD) in a prospective population-based cohort. Background: Sleep disturbances such as daytime sleepiness are frequent in PD.…Longitudinal evolution of excessive daytime sleepiness in early Parkinson’s disease
Objective: To examine longitudinal change in excessive daytime sleepiness (EDS) in the cohort of at baseline de novo Parkinson's disease (PD) subjects. Background: We have…Patient-centered educational intervention using hand-held electronic devices
Objective: To examine feasibility, usability and initial efficacy of an e-learning intervention, using an interactive tablet-based slideshow with audio/video and quizzes. Background: Mobile tablet and…Development and external validation of a prognostic model of mortality in Parkinson’s disease
Objective: To develop and validate a prognostic model to predict mortality in Parkinson's disease (PD). Background: Most previous prognostic studies in PD have used unrepresentative…Evaluation of the [ 99mTc] – TRODAT- 1 SPECT in the diagnosis of Parkinson’s disease and other movement disorders
Objective: Evaluation of the [ 99mTc] - TRODAT- 1 SPECT in the diagnosis of PD and other MD. Create a DATA bank for our population.…Patients’ employment status and quality of life affect caregivers burden in Parkinson’s disease in Singapore
Objective: This study was aimed at assessing caregiver burden (CB) and analyzing its relationship with patient's sociodemographic, motor and non-motor severity as well as health-related…
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