GLA-associated early-onset Parkinson’s disease: the mimicry between Fabry disease and parkinsonisms
Objective: To characterize an early-onset Parkinson’s disease (EOPD) patient with atypical clinical phenotype. Background: Genome sequencing is allowing new Parkinsonian Syndromes (PS)-associated genes identification. However,…Reversible secondary parkinsonism attributed to metformin-induced lactic acidosis
Objective: We describe the case of a 59-year-old man who was evaluated for abnormal imaging and subacute parkinsonism. Background: Secondary parkinsonism can be caused by…Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder
Objective: The goal of this study was to investigate the feasibility of deep learning in the prediction of disease conversion in RBD patients. Background: Rapid…Feasibility Of An Intensive Inpatient Parkinson’s Rehabilitation Program For Moderately Advanced Parkinson’s Disease
Objective: To determine the feasibility in the US of a multimodal intensive inpatient Parkinson’s Rehabilitation program for patients with moderately advanced Parkinson’s disease (PD) Background:…Presynaptic dopamine compartmentalization defects initiate auxilin-mediated parkinsonism
Objective: To evaluate the pathogenic mechanisms for auxilin-mediated Parkinson’s disease (PD). Background: Auxilin participates in uncoating of clathrin-coated vesicles (CCVs), thereby facilitating synaptic vesicle (SV)…Protective effects of Hibiscus sabdariffa extracts in 6-hydroxydopamine-lesioned parkinsonism.
Objective: The therapeutic effects of Hibiscus sabdariffa (HS) were investigated in parkinsonism rats induced by 6-hydroxydopamine (6-OHDA). Background: The oxidative stress is an important component…The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson’s Disease
Objective: To determine the feasibility and impact of remote cognitive remediation therapy (CRT) on cognitive function and quality of life (QOL) in patients with Parkinson’s…Diagnostic value of striatal [18F]-FP-DTBZ PET in Parkinson’s disease
Objective: To detect the difference of dopaminergic integrity between PDs and healthy controls (HC) using [18F]-FP-DTBZ PET in vivo and to obtain the diagnostic value…Amelioration of Levodopa-induced Dyskinesias using Genetic Silencing of Striatal CaV1.3 in Parkinsonian Rats: Impact of Sex and Advancing Age
Objective: To advance understanding of striatal CaV1.3 (cacna1d) channel silencing as a therapeutic approach to reduce levodopa-induced dyskinesias (LID), a side effect of long-term escalating…Activity and sleep associated with changes in glymphatic imaging-markers in Parkinson Disease patients enrolled in 3-month exercise program
Objective: To investigate whether intensity of activity and quality of sleep during a 3-month exercise program for patients with Parkinson Disease (PD) are associated with…
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