Fall prediction in Parkinson’s disease based on motor dual-tasking: Evidence from the prospective MODEP study
Objective: To evaluate the predictive value of dual-task performance for future falls in patients with Parkinson's disease (PD). Background: Falls entail very severe health-related consequences…Neuropsychiatric, personality and non-motor correlates of impulse control disorders in recent onset Parkinson’s disease
Objective: To record the prevalence and clinical correlates of impulse control disorders (ICDs) in recent onset Parkinson's disease (PD) cases in the Tracking Parkinson's (PRoBaND)…A new tool to stage Parkinson’s disease PDCS (Parkinson’s disease composite scale): A pilot study on behalf of the European Parkinson’s disease association (EPDA)
Objective: The aim of PDCS is to create a simple scale able to measure the severity of patients, taking into account cardinal motor, non motor…Pantotenate kinase associated neurodegeneration (PKAN): Proposal for a clinical rating scale
Objective: To design and validate a quantitative method for the assessment of PKAN patients. Background: Despite advances in the research of novel therapies for PKAN,…Syndrome of dystonia-parkinsonism is a complication of cyclosporine A treatment and may be irreversible
Objective: To describe the clinical and imaging features of patients who developed dystonia-parkinsonism syndrome due to cyclosporine A(CsA). Background: CsA is an immunosuppressant widely used…A comparison of standards of care in Parkinson’s disease between a general neurology clinic and a specialist movement disorders clinic based on the UK NICE guidelines
Objective: To compare standards of care for patients with Parkinson's disease (PD) between a general neurology clinic and specialist movement disorders clinic based on the…Elemental profiles as biomarkers for diagnosis and disease progression of Parkinson’s disease
Objective: This study aims to analyse the elemental profiles in the cerebrospinal fluid (CSF) of patients with idiopathic Parkinson´s disease (PD) and age-matched control patients…PERFORM: Controlled study in fluctuating PD patients examining the effects of motor state on the outcomes resulting from a structured physical therapy (PT) program
Objective: To determine if outcomes following a PT program are improved if PT sessions are conducted while PD patients are in an on motor state…Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
Objective: To explore the potential use of alpha-synuclein (α-syn) species as candidate biomarkers for Parkinson's disease (PD). Background: Despite decades of intensive research, to date,…A randomized controlled clinical study to evaluate efficacy, safety and tolerability of SC L-dopa/carbidopa (ND0612H) infusion regimens in fluctuating PD patients
Objective: To evaluate the efficacy, safety & tolerability of continuous subcutaneous infusion regimens of ND0612H. Background: L-dopa remains the most effective PD medication, however oral…
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