Taking specialist clinics into community nursing homes
Objective: Evaluate the effectiveness of delivering specialist Parkinson's care in community care home settings. Background: Our drive to improve older people's care has led to…Combined stimulation of STN and SNr for resistant freezing of gait in Parkinson’s disease (STN+SNr) – A multicenter randomized controlled trial
Objective: 54 patients with idiopathic Parkinson's disease and freezing of gait resistant to subthalamic nucleus stimulation and dopaminergic medication will be included into this German-wide…DBS targeting: Validation of 3T MR image guided targeting using post-mortem 17T MR microscopy
Objective: This work helps validate the utility of direct targeting using 3T T1 inverted sequences with atlas application during planning for DBS electrode placement. We…Role of contact polarity on therapeutic impedances at two deep brain stimulation (DBS) targets
Objective: To demonstrate the role of contact polarity on therapeutic impedances at two DBS targets. Background: Neuromodulation with DBS is an established therapy for medically…A prospective study of patients’ expectations in subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To prospectively assess the long-term outcome of subthalamic nucleus (STN) deep brain stimulation (DBS) and the relationship with patients' expectations and satisfaction. Background: Subthalamic…Cognitive change following deep brain stimulation in patients with movement disorders
Objective: To assess the degree and pattern of cognitive changes following Deep Brain Stimulation (DBS) in patients with Parkinson's disease (PD), Dystonia and Essential Tremor…Mild Parkinsonian signs and TIA/stroke
Objective: We aimed to determine if MPS increases TIA/stroke risk. Background: Mild Parkinsonian signs (MPS) are a syndrome of mild basal ganglia dysfunction characterized by…Dementia in Parkinson’s disease is associated with increased diffusivity in amygdala and external capsule
Objective: To identify which regions are associated with dementia in Parkinson's disease (PD) brains. Background: Dementia is common in advanced PD and its early development…Cognitive profile in the Parkinsonian variant of multiple system atrophy: Findings from a Tunisian cohort
Objective: To establish the cognitive profile of MSA-P in a Tunisian cohort and to discuss its association with motor signs. Background: It has been previously…LRRK2, MAPT and HTRA2 mutations in the pedigree of familial neurodegenerative parkinsonism with cognitive deterioration spanning five generations in a genetically isolated population of south-eastern Moravia, Czech Republic
Objective: To obtain genetic information about the individuals with confirmed parkinsonism in an isolated rural region in south-eastern Moravia, Czech Republic. Background: An epidemiological study…
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