Behavior and PET Imaging Study in Parkinsonian Rat Models Induced by Injection of 6-OHDA in Medial Forebrain Bundle
Objective: To employ behavioral test, positron emission tomography (PET) imaging and immunohistochemical staining to assess the changes of brain function and dopaminergic system in rat…Multi-echo GRE and DTI MR imaging of the Substantia Nigra in early Parkinson’s disease: A pilot 1-year prospective controlled study
Objective: To assess the sensitivity of multi-echo GRE and DTI MR imaging to changes in Substantia Nigra (SN) in early Parkinson’s disease (PD) Background: In…The Gut Microbiota in a Canadian Parkinson’s Disease Cohort
Objective: To compare the gut microbiota between PD patients and matched controls in a Canadian cohort and to examine correlations between microbes and disease parameters…The Effect of Sleep Deprivation on Short-Term Memory and Emotion of Rotenone Treated Zebrafish Model of Parkinson Disease
Objective: We investigated the long-term consequences of sleep deprivation on short-term memory and emotion using a rotenone treated zebrafish model of Parkinson disease. Background: Parkinson…Weight loss is associated with rapid striatal dopaminergic degeneration in Parkinson’s disease
Objective: To investigate whether weight loss has a longitudinal association with striatal dopaminergic degeneration in Parkinson's disease (PD). Background: Weight loss in PD is associated…Sleep, Fatigue and Health-related quality of life in a cohort of Parkinson disease patients
Objective: To determine frequencies of non-motor symptoms (NMS) specifically sleep disorders, fatigue and mood disorders in a cohort of Nigerians with PD seen at the…α-synuclein aggregation and propagation in marmoset brains deteriorates its motor function
Objective: To confirm that α-synuclein aggregation and propagation in marmoset brains deteriorates its motor function. Background: Recently, the α-synuclein amyloid fibril is thought to be…Deletion of GBA2 in neuronopathic Gaucher’s disease medaka can’t rescue the phenotype
Objective: This study was performed to determine the pathological role of GBA2 in the CNS in GD and GBA1-related PD. Background: Parkinson’s disease (PD) is…Classification of Dopaminergic-State and Motor Activity by Theta, Beta and Gamma Activity in Parkinson’s Disease
Objective: To test whether machine learning algorithms are suitable to classify dopamine and behavioral states in Parkinson’s patients (PD). Background: While motor symptoms of PD…Depression and associated factors in nondemented Chinese patients with Parkinson’s disease
Objective: This study aimed to estimate the prevalence and identify potential risk factors influencing depression in 519 consecutive nondemented Chinese PD patients. Background: Depression is…
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