Smartphone App-Based Assessment of Gait in patients with Parkinson’s disease
Objective: The purpose of this pilot study was to determine if gait metrics derived from the App correlated with clinical symptoms and functional performance in…The impact of a wearable device on Parkinson’s disease motor symptom management in patients starting rotigotine transdermal patch
Objective: Open-label, multi-center pilot study (PD0049) to evaluate the impact of Kinesia 360 (an “at home” wearable device) on motor symptom management in Parkinson’s disease…FXTAS-like Phenotype with p.P626L Missense Mutation: A case report
Objective: To describe p.P626L missense mutation of FMR1 gene in a patient with clinical phenotype of Fragile X Associated Tremor and Ataxia Syndrome (FXTAS). Background:…A promising model for cognitive dysfunction in Parkinson’s Disease by AAV-mediated alpha-synuclein overexpression in hippocampus
Objective: Our aim is to model cognitive dysfunction of Parkinson's disease (PD) together with motor deficits by targeted overexpression of alpha-synuclein (a-syn) in bilateral dentate…PLA2G6-related juvenile-onset Parkinsonism: clinical features and cognitive profile in a cohort of Chinese patients
Objective: Among young or juvenile onset Parkinson (PD) patients, we assessed cognitive and clinical performances, comparing homozygotes and compound heterozygotes who carry PLA2G6 pathogenic mutations…Association analysis of miRNA-linked variants with Parkinson’s disease and multiple system atrophy in a large Chinese population
Objective: To explore the relationship between two miRNA-linked variants (SPPLB rs1128402 and PDXK rs2070535) and two neurodegenerative diseases (PD and MSA) in a large Chinese…Identification and analysis of differential miRNA in exosomes of dopaminergic neurons overexpressing α-synuclein
Objective: The aim of this study was to compare the miRNA expression in secreted exosomes from dopaminergic neurons overexpressing α-synuclein with healthy neurons. Background: Exosomes,…Quantitative analysis of DaT uptake and neuromelanin MR contrast in patients with Parkinson’s disease and healthy controls
Objective: To examined quantitative measures of neuromelanin (NM) MRI and DaT-SPECT imaging of the SN and striatum to distinguish PD patients from healthy control subjects…Paraneoplastic and neuronal surface antibodies in Parkinson’s disease and atypical parkinsonian disorders
Objective: To investigate the prevalence of paraneoplastic and antineuronal antibodies in the serum and cerebrospinal fluid (CSF) from patients with Parkinson´s disease (PD) and atypical…Mineralization pattern of the deep gray matter by susceptibility-weighted magnetic resonance imaging to differentiate Parkinsonian disorders
Objective: To study mineralization pattern of the deep gray matter by susceptibility-weighted (SWI) magnetic resonance imaging to differentiate Parkinson’s disease and atypical parkinsonian disorders like…
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