Differential diagnosis of Parkinsonian Syndromes – combining clinical and imaging data in a machine-learning approach
Objective: To assess the feasibility of automated classification of different parkinsonian subtypes using clinical and imaging variables in a single center study. Background: The clinical…Automated Diagnosis of Idiopathic Parkinson’s Disease Using Deep Convolutional Neural Networks
Objective: The aim of this study is to implement and evaluate CNN-based DL approach for the diagnosis of IPD. We trained CNNs on a…EEG guided neurofeedback boosts effects of motor cortex neuromodulation of rTMS in Parkinson´s Disease Patients
Objective: To compare the clinical and neurophysiological effects of EEG guided Neurofeedback (NFB) vs 10Hz rTMS vs combined therapy (NFB+rTMS) in motor cortex of non-demented…Four square step test in patients with early de novo Parkinson’s disease
Objective: The Four Square Step Test (FSST) is brief and easy tool to assess dynamic balance to step over hindrance. Originally developed for older adults,…Design and Baseline Characteristics of an Open-Label, Randomized, 26-Week Study Comparing Levodopa-Carbidopa Intestinal Gel to Optimized Medical Treatment on Non-Motor Symptoms in Patients with Advanced Parkinson’s Disease – INSIGHTS Study
Objective: To evaluate the effectiveness of levodopa-carbidopa intestinal gel, LCIG (known as carbidopa-levodopa enteral suspension in the US), on non-motor symptoms (NMS) compared with optimized…Effects of Virtual Reality Exercise Program using the Sony PlayStation 2 gaming platform on Balance, Emotion and Quality of Life in Patients with Parkinson’s Disease
Objective: This study was to investigate the effectiveness of a 12-week virtual reality(VR) exercise program designed around low-cost VR device, the Sony PlayStation 2 (PS2) gaming…Management of Akinesia in Parkinson’s Disease with Apomorphine Subcutaneous Injection
Objective: To assess the effect of apomorphine on time-to-ON in PD patients with morning akinesia. Background: In patients with motor fluctuations complicating Parkinson's disease (PD), delays in time-to-ON…Imaging Parkinson’s disease pathology: A comparison between neuromelanin-sensitive MRI, susceptibility weighted imaging and [11C]PE2I DAT PET
Objective: We compared 2 novel MRI techniques: neuromelanin-sensitive MRI (NM-MRI) and susceptibility weighted imaging (SWI) with [11C]PE2I PET in order to establish their validity as biomarkers…The effect of ADORA2A gene polymorphism on the dyskinesia of Parkinson’s Disease
Objective: To investigate the relationship of levodopa-induced dyskinesia with ADORA2A gene polymorphisms in PD patients. Background: With the progression of the disease, motor complications and…Genetic panel testing in Parkinson’s disease
Objective: To evaluate effectiveness of panel testing of known Parkinson's disease (PD) related genes in clinical practice. Background: It is widely recognised that monogenic forms…
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