Construct validity of the Movement Disorders Society – Non Motor Rating Scale (MDS-NMS)
Objective: To analyze the construct validity of the Movement Disorders Society – Non Motor Rating Scale (MDS-NMS). Background: The MDS-NMS is a new instrument that…The influence of baseline body mass index on cognitive decline in Parkinson’s disease
Objective: The aim of this study is to know whether the baseline BMI is associated with cognitive decline and future development of dementia. Background: Alterations…Connectivity alterations in dopaminergic and cholinergic networks mediate cognitive performance in patients with Parkinson’s disease: a resting-state fMRI study
Objective: To explore changes in resting-state fMRI (rs-fMRI) functional connectivity networks in PD patients, in areas with prominent dopaminergic and cholinergic innervation. Background: The pathophysiology…Glymphatic system activity in Parkinson’s disease: diffusion tensor image analysis along the perivascular space (DTI‑ALPS)
Objective: We examined the activity of the glymphatic system in patients with Parkinson’s disease using diffusion tensor image analysis along the perivascular space (DTI-ALPS). Background:…Preserved white matter microstructure in Parkinson’s disease patients with levodopa-induced dyskinesia: Evaluation by neurite orientation dispersion and density imaging (NODDI)
Objective: Brain microstructure alteration using MRI in Parkinson's disease (PD) have not been well studied. We analysis the white matter alterations in Parkinson’s disease with…Longitudinal Change of Substantia Nigra Hyperechogenicity in Parkinson’s Disease Cohort
Objective: To analyze whether the size of SN+ is differentially affected depending on disease duration. Secondly to analyze the interaction between a range of clinical…Kick Out PD: Mobility, Quality of Life, and Feasibility Outcomes in a Pilot Study of a PD-Specific Karate Intervention
Objective: To evaluate feasibility of a community-based karate class tailored for individuals with early- to middle-stage Parkinson’s Disease (PD); to assess effect of karate on…Predicting the efficacy of STN-DBS in patients with different Parkinson’s disease motor subtypes by preoperative total and partial levodopa response
Objective: To better investigate the value of the challenge test by introducing total and partial LR, and explain the clinical significance of 30% LR through…Safety and Tolerability in Parkinson’s Disease Patients Treated with a Continuous Subcutaneous Infusion of ABBV-951: Design of a 52-Week Phase 3 Study
Objective: To assess the local and systemic safety and tolerability of ABBV-951 delivered as a continuous subcutaneous infusion (CSCI) for 24 hours daily for up…Safinamide: real world evidence in Toledo´s Movement Disorders Unit
Objective: We present a prospective observational-real life study about the use of safinamide in Movement Disorders Unit´s patients. Background: The gold standard of pharmacological treatment…
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