Therapeutic management of complicated Parkinson’s disease: clinical application of the Motor Fluctuation Indices
Objective: To evaluate the usefulness of the Motor Fluctuation Indices to assess clinically relevant change in motor fluctuations in advanced Parkinson’s disease (PD) patients after…Characteristics of gait and quality of life in Parkinson’s disease
Objective: To find the independent correlation between characteristics of gait and QoL in PD, comprehensive assessment of clinical characteristics and objective gait analyses were done…Serum uric acid levels and cognitive function in Parkinson’s disease
Objective: To compare serum uric acid (sUA) levels in Parkinson’s disease (PD) subjects to cognitive function. Background: Reduced sUA levels have been reported in individuals…Incidence of drooling in Parkinson’s Disease and Impact on Quality of Life
Objective: The project aimed to determine the frequency and severity of drooling in the Parkinson’s Disease (PD) population in Cardiff & the Vale Health-board through…Impaired lysosomal catabolism of alpha-synuclein in parkinsonian LRRK2(R1441G) mutant mouse embryonic fibroblasts
Objective: Using a unique fluorescence-based flow cytometry assay on LRRK2(R1441G) mutant mouse embryonic fibroblasts (MEFs) to elucidate whether pathogenic LRRK2 mutation affects cellular lysosomal degradation…Attitude of Parkinson Patients towards Participation in Clinical Trials and Brain or Tissue Donation for Research
Objective: A comprehensive survey of patient preferences and attitudes towards clinical trials and tissue donation can help identify and address barriers hindering the recruitment for…Beneficial effect of estrogen on nigrostriatal dopaminergic neurons in drug-naïve postmenopausal Parkinson’s disease
Objective: To investigate the potential beneficial effects of estrogen on nigrostriatal dopaminergic neuron degeneration in postmenopausal drug-naïve Parkinson’s disease. Background: Epidemiologic studies have revealed that…Machine learning classifiers and subjective vocal perception of Parkinson’s disease patients and healthy control
Objective: To identify machine learning classifiers and to assess the acoustic differences between PD patients and healthy control (HC) and the relations between objective and…Phenotypic spectrum of Progressive Supranuclear Palsy in a Tunisian cohort
Objective: To describe the clinical and imaging features of the different phenotypes of progressive supranuclear palsy (PSP). Background: PSP is a neuropathologically defined disease entity…Liquid Levodopa/Carbidopa – An underutilized, cost effective treatment of advanced Parkinson’s disease in the developing world
Objective: Advanced Parkinson’s disease manifests with “on-off” phenomenon, dyskinesias and increasing symptom severity . Managing it in developing countries is difficult given the low per…
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