Progression of dopaminergic and serotonergic dysfunction related to motor and nonmotor manifestations in apathetic and non-apathetic parkinsonian patients: a 4-year longitudinal double-tracer PET study
Objective: To investigate the progression of dopaminergic and serotonergic dysfunction and their relation to motor and nonmotor impairment in parkinsonian patients with or without apathy,…Non-Invasive Vagus Nerve Stimulation: A non-pharmacological approach to target gait impairment in Parkinson’s disease?
Objective: To determine whether single dose non-invasive vagus nerve stimulation (nVNS) enhances gait performance in Parkinson’s (PD). Background: Loss of cholinergic neurons from nucleus basalis…An explorative study on the value of clinical features for diagnosing Parkinson’s disease
Objective: To investigate the usefulness of clinical features to differentiate subjects with “scans without evidence of dopaminergic deficit” (SWEDD) from patients presumed to have Parkinson’s…Long-term impact of Levodopa Carbidopa Intestinal Gel (LCIG) on reducing “Off” time: Results from a systematic review of studies with ≥ 12 months of follow-up
Objective: The objective of this study was to summarize evidence evaluating long-term (i.e. ≥ 12 months)efficacy of levodopa carbidopa intestinal gel (LCIG) on “off” time,…Changes to Speech Production after SpeechVive Treatment in Individuals with Parkinson’s Disease
Objective: The purpose of the present study was to assess the effects of a device-driven treatment (SpeechVive) on respiratory and laryngeal function after 8 weeks…Continuous circadian intracerebroventricular administration of anaerobic dopamine: A new therapeutic concept for Parkinson’s disease?
Objective: We aim to overcome these challenges by demonstrating that continuous i.c.v. of Anaerobic-dopamine (A-dopamine,Patent #WO2015173258 A1) close to the striatum is a feasible and…Yerba mate tea (Ilex paraguariensis) exerts a neuroprotective effect on intrastriatal 6-OHDA-lesioned mice model of Parkinson’s disease
Objective: We set to investigate the possible neuroprotective effect of yerba mate (YM) consumption on dopaminergic neurons in a mice model of Parkinson’s disease (PD). Background: The motor…Progression of neuropsychiatric symptoms in Parkinson’s disease
Objective: To determine the progression of neuropsychiatric symptoms (NPS) in Parkinson’s disease (PD) and their associations with quality of life (QoL) and motor problems. Background:…Comparison of Gene Expression in Parkinson’s Disease and Bipolar Disorder
Objective: The aim of this research is to compare the overexpressed genes in patients with Parkinson's Disease (PD) and patients with Bipolar Disorder (BD) versus…Prevalence of Fabry disease among patients with Parkinson’s disease
Objective: To determine the prevalence of Fabry disease (FD) among patients with Parkinson’s disease (PD). Background: Increased prevalence of PD disease has been previously reported…
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