Case Report: Co-occurrence of Motor Neuron Disease and Parkinsonism
Objective: Explore possible links between degenerative parkinsonism and motor neuron disease Background: A 50 year-old man developed with the cardinal features of parkinsonism. History was…Peripheral Blood Mononuclear Cells (PBMCs) are Useful Biomarkers of Mitochondrial Dysfunction in Parkinson Disease Patients with Pathogenic Parkin and LRRK2 Mutations
Objective: To investigate the use of PBMCs as a biomarker of mitochondrial dysfunction in Parkinson disease (PD) patients carrying pathogenic parkin or LRRK2 mutations. Background:…Neuroanatomical and clinical predictors of pain in patients with early de novo Parkinson’s disease
Objective: We investigated associations between clinical features, neuroanatomical changes and pain in early de novo Parkinson’s disease (PD) patients. Background: Pain is a common and…Hip fracture in patients with a new diagnosis of Parkinson’s Disease – estimating the 5-year risk
Objective: We set out to quantify the five-year risk of hip fracture for a cohort of 780 patients for whom a new diagnosis of Parkinson’s…Bilateral vestibulopathy due to neurosarcoidosis mimicking Parkinsonian syndrome
Objective: We here describe a patient with neurosarcoidosis presenting with progressive gait disturbance that mimics Parkinsonian syndrome. Background: Neurosarcoidosis can show various neurological complications; however,…Impact of OFF periods on aspects of employment for people with Parkinson’s disease
Objective: To characterize the impact of OFF periods on aspects of employment for people with Parkinson’s disease (PD) who have OFF periods compared to those…Serum uric acid level as a biomarker in sporadic and familial (p.A53T alpha synuclein carriers) Parkinson’s disease: Longitudinal data from the PPMI study
Objective: To determine whether there are longitudinal differences in serum uric acid level among sporadic Parkinson’s disease (PD) patients, PD patients harboring the p.A53T mutation…Corneal confocal microscopy: An imaging biomarker of neurodegeneration in Parkinson’s disease
Objective: The aim of the study is to investigate whether corneal confocal microscopy (CCM) can be used as a rapid, reliable, automated and non-invasive method…The Oral Metagenome and Metatranscriptome of Early Stage Parkinson’s Disease and their Relationship with Clinical and Functional Outcome Measures of Motor and Nonmotor Function
Objective: To identify sensitive and specific biomarkers of changes in the oral microbiome of subjects with early stage Parkinson’s Disease and relate these to clinical,…Glabellar tap predicts dopamine transporter deficiency in parkinsonism
Objective: The objective of this study was to investigate the association between glabellar tap findings with nigrostriatal dopamine function in patients with unclear parkinsonism. Background:…
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