The association parkinsonism and psychotic symptom in neurosyphilis
Objective: To report the cases of neurosyphilis revealed by the association parkinsonism and psychotic symptom. Background: The NS is the "great imitator" because it can…Variants in the beta-Glucocerebrosidase A (GBA) gene in German patients with Parkinson´s disease
Objective: To characterize GBA variants in a cohort of German patients with PD. Background: GBA encodes the lysosomal enzyme beta-glucocerebrosidase A. GBA mutations cause the lysosomal…Effect of polygenic load on striatal dopaminergic deterioration in Parkinson’s disease
Objective: To investigate the longitudinal association between PD-associated polygenic load and the striatal dopaminergic activity using 123I-N-3-fluoropropyl-2-beta-carboxymethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) single photon emission computed tomography (SPECT).…Rapidly onset progressive generalised dystonia parkinsonism in a young Indian male with rare FBXO 7 genetic mutation
Objective: To describe a rare case of rapidly progressive generalized dystonia parkinsonism due to FBXO7 gene mutation. Background: Parkinson’s disease is a neurodegenerative disorder of…Severity of REM sleep without atonia (RSWA) correlates with cognitive functions in patients with REM sleep behaviour disorder (RBD)
Objective: to assess the correlations between the severity of RSWA and cognitive functions in patients with RBD, both isolated (iRBD) and associated to Parkinson’s Disease…The influence of relationship quality on health-related quality of life when coping with Parkinson’s disease: a mediation analysis
Objective: To explore motor and non-motor symptoms (NMS) influence on relationship quality (mutuality) and health-related quality of life (HRQoL) when one in the dyad is…Share the Care: Supporting Parkinson’s Disease Caregivers Through Peer Mentoring
Objective: To describe the design and implementation of a novel caregiver peer mentoring program for caregivers of patients with advanced PD. Background: As PD progresses,…Immediate effect of the virtual and augmented reality and neurofunctional physiotherapy on postural control and cognition in patients with Parkinson’s disease: a randomized clinical trial
Objective: To evaluate the immediate effect of augmented reality (AR), virtual reality (VR) and neurofunctional physiotherapy (NP) in postural control and cognition of patients with…Preliminary validation of a novel, comprehensive digital biomarker smartphone application to assess motor symptoms in de-novo diagnosed Parkinson patients
Objective: To determine the reliability and validity of a novel, comprehensive digital biomarker remote monitoring approach to actively and passively measure motor symptom progression in…Gender differences in Motor symptoms, Non-Motor symptoms and Quality of Life in Parkinson’s disease: COPPADIS-2015 study cohort
Objective: To assess gender differences among PD patients and health controls (HC) of the COPPADIS-2015 study cohort. Background: Men and women are different in genetic,…
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