Is safinamide helpful in multiple system atrophy?
Objective: To retrospectively review the clinical benefit of safinamide in patients with Multiple System Atrophy. Background: Safinamide is a new monoamine oxidase-B inhibitor, with dopaminergic…The effects of zonisamide on motor and non-motor symptoms in patients with Parkinson’s disease: a 3-month open-label study
Objective: To investigate the effect of zonisamide (ZNS) on motor and non-motor symptoms, such as depressive symptoms and sleep problems, in patients with Parkinson’s disease…Lip movement contribution in speech production of persons with Parkinson’s Disease
Objective: Lip movements contribute to communication by producing labial sounds, conveying facial expression and aiding visually in speech perception. This study planned to understand lip-movements…Automated Quantitative MRI Biomarkers in Differentiation of Progressive Supranuclear Palsy and Multiple System Atrophy from Parkinson Disease
Objective: To explore the relative merits of automated MRI-based volumetric measures over visual assessment in the differential diagnosis of Parkinson's disease (PD), parkinsonian variant of…Modeling the Effect of Patient’s Perception of Non-Motor and Motor Function on Parkinson’s Disease Severity
Objective: To develop optimal models of patients' perception of non-motor and motor function on objectively measured Parkinson's disease (PD) severity. Background: There is increased interest…Tsallis entropy of EEG correlates with future cognitive decline in patients with Parkinson’s disease
Objective: To evaluate whether Tsallis entropy (TE) constitutes a possible functional characterization of neurodegeneration and a measure to predict progression of Parkinson’s disease (PD). Background:…How cognitive effort increases Parkinson’s tremor – an effictive connectivity fMRI study
Objective: To elucidate the neural mechanisms underlying tremor amplification during cognitive effort. Background: Parkinson’s tremor is related to cerebral activity in both basal ganglia and…Motor and non-motor symptoms differences between Vascular Parkinsonism (VP) and Parkinson’s Disease (PD) patients in early stages
Objective: Compare motor and non-motor symptoms between VP and PD patients. Background: VP is usually described as “lower-body parkinsonism”, with early gait difficulties and postural…Characterizing olfactory impairment in patients with Parkinson’s disease and related disorders
Objective: To characterize olfactory impairment in Parkinson’s disease (PD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Background: In the previous study, we found…Impaired fonction of mirror neurons and the role of levodopa in PD patients
Objective: Study of the emotional mirroring and its modulation by levodopa treatment in fluctuating PD patients with no significant cognitive burden as assessed by regular…
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