Evaluation of Proactive and Integrated Management and Empowerment in Parkinson’s Disease (PRIME Parkinson) in The Netherlands a prospective observational study
Objective: We will evaluate the utility of PRIME Parkinson care on a single primary endpoint (parkinsonism-related complications), which reflects the Population Health dimension, and on…Regional cortical thickness alterations in PD patients with cognitive impairment
Objective: To evaluate the cortical thickness alterations in cognitively impaired patients with PD (PD-CI) in a comparative study with cognitively normal patients with PD (PD-CN)…Information processing components in Parkinson’s disease with and without impulse control disorders: identification of diagnostic and predisposition markers
Objective: To search for differences in specific components of cognitive processing in Parkinson’s disease (PD) patients with and without impulse control disorders (ICD) in order…First clinical and genetic analysis of LRRK2 G2019S, R1441G/C/H/, I2020T and Y1699C mutations in Costa Rican patients with Parkinson’s disease
Objective: To assess the frequency of G2019S, R1441G/C/H, I2020T and Y1699C mutations in a Costa Rican cohort of Parkinson’s disease (PD) cases and controls. Background:…Neurodevelopmental disorder and parkinsonism in a patient with WDR45 variant: a long-term outcome
Objective: To expand the clinical spectrum of WDR45 deficiency. Background: Beta-propeller protein-associated neurodegeneration (BPAN) due to WDR45 defect is a rare X-linked dominant disorder of…H1/H2 MAPT Haplotype and Parkinson’s Disease in an Ashkenazi Jewish Cohort
Objective: To study the Microtubule-Associated Protein Tau (MAPT) H1/H2 haplotype contribution to clinical manifestation of Parkinson’s disease (PD) in an Ashkenazi Jewish (AJ) cohort, focusing…Clinical and Genetic Characteristics of the University of Pennsylvania Parkinson’s Disease Population: Results from the Molecular Integration in Neurological Diagnosis (MIND) Initiative
Objective: To describe the clinical characteristics and the frequency of GBA and LRRK2 variants in the Parkinson’s disease (PD) patient population at The University of…Deep learning-based automatic nigrosome 1 segmentation on 3T susceptibility-weighted MRI
Objective: The aim of this study was to develop a deep learning-based system for automatic nigrosome 1 segmentation on susceptibility-weighted imaging (SWI) from 3T magnetic…The clinical significance of the swallow tail sign in distinguishing Parkinson’s disease patients from healthy individuals
Objective: To investigate whether the absence of the swallow tail sign can be applied for distinguishing PD patients from healthy individuals. Background: With conventional MRI,…Dysfunction in superior frontal gyrus associated with diphasic dyskinesia in Parkinson’s disease
Objective: We aimed to explore alterations in regional brain function associated with diphasic dyskinesia in Parkinson’s disease (PD). Background: Levodopa-induced dyskinesia (LID), which is a common…
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